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Optogenetic stimulation of serotonin neurons in the dorsal raphe causes mice to move more slowly without causing any apparent motor deficits or anxiety-like effects.

Molecular genetic experiments are revealing how the fly brain generates behavioral responses to visual stimuli.

A molecule called microRNA-153 helps to prevent rats associating new environments with fear.

A small molecule called Sm4 can disrupt interactions involving a transcription factor called Sox18, while having little impact on other members of the SoxF family.

Personalized heart muscle cells made from stem cells in the laboratory could be used to check an individual’s response to potential new drugs before clinical trials.

RNA molecules cause the proteins involved in the formation of germ granules to coalesce into liquid droplets.

Human cells that lack a subunit in their origin recognition complex are viable, which suggests the existence of alternative mechanisms to initiate DNA replication.

Targeting the transcription factor c-Myc via one of its coactivator proteins is a promising strategy for cancer therapy.

Biological variability has confounded efforts to confirm the role of PREX2 mutations in melanoma.

Experimental efforts to validate the output of a computational model that predicts new uses for existing drugs highlights the inherently complex nature of cancer biology.