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19,302 results found
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Structures of LolB bound to LolA or lipoprotein resolve the final steps of bacterial lipoprotein trafficking

    Abigail E Jepson, Elise Kaplan ... Vassilis Koronakis
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Evolutionary Biology

    Sequence adaptations satisfy the constraints of mitochondrial membrane protein evolution

    Tarun Yadav, Jonathan H Borowsky ... Jared Rutter
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Cancer Biology

    P95-HER2 promotes metastatic progression by biasing MRTFA dependent signaling

    Joseph D Fernandes, Erin Bresnahan ... Joshua C Snyder
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Glutamate receptor composition at Drosophila neuromuscular junctions depends on developmental stage and muscle identity

    Anne Sustar, Chengjie Qiu ... John C Tuthill
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Neuroscience

    A validated antibody toolbox for ALS research

    Riham Ayoubi, Emma J MacDougall ... Carl Laflamme
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    The time course of neural activity predictive of self-initiated movement

    Lucas Jeay-Bizot, Mehmet Basbug ... Aaron Schurger
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Plant Biology

    AT-HOOK-MOTIF NUCLEAR LOCALIZED 15 extends plant longevity by binding at poorly accessible, epigenetic mark-depleted chromatin surrounding transcribed regions

    Thalia Luden, Jihed Chouaref, Remko Offringa
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Computational and Systems Biology

    Role of desolvation on biomolecular liquid–liquid phase separation

    Kai Zhang, Zhiyu Peng ... Wei Wang
    A desolvation-aware coarse-grained framework enables efficient and physically realistic modeling of biomolecular phase separation by capturing water-mediated effects on phase behavior, dense-phase packing, conformational reorganization, and dynamics.
    1. Microbiology and Infectious Disease

    The structural context of mutations in proteins predicts their effect on antibiotic resistance

    Anna G Green, Mahbuba Tasmin ... Maha Reda Farhat
    Spatial clustering of mutations in Mycobacterium tuberculosis proteins finds proteins that are involved in antibiotic resistance, and predicts which mutations cause resistance.
    1. Genetics and Genomics
    2. Neuroscience

    Starvation transforms signal encoding in C. elegans thermoresponsive neurons and suppresses heat avoidance via bidirectional glutamatergic and peptidergic signaling

    Saurabh Thapliyal, Parvathi Sushama Gopinath, Dominique A Glauser
    Nutritional state dynamically reshapes sensory processing to prioritize behavioral responses, revealing the plastic coupling of sensation, internal state, and behavior.
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