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  1. A hand gloved in blue holding a magenta spark on a grey background

    Health: Reading our future in the bones of children past

    As the United Kingdom braces for a sharp fall in living standards, a bioarchaeologist and a paediatrician discuss what the past can reveal about the social forces that shape modern health crises.
    1. Cell Biology
    2. Immunology and Inflammation

    Phagocytosis: The central role of the centrosome

    Isabel Stötzel, Eva Kiermaier
    The centrosome decides which branch extending from the body of microglia will successfully engulf and clear away dead neurons.
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    1. Structural Biology and Molecular Biophysics

    Antibiotics: Teaching old drugs new tricks

    Alexandre Faille, Alan J Warren
    Understanding the mechanism by which streptomycin binds to the small subunit of the mitoribosome may help researchers design less toxic derivatives of this antibiotic.
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  2. Point of View: eLife’s new model and its impact on science communication

    Lara Urban, Mariana De Niz ... Lamis Yahia Mohamed Elkheir
    The eLife Early-Career Advisory Group discusses eLife’s new peer review and publishing model, and how the whole process of scientific communication could be improved for the benefit of early-career researchers and the entire scientific community.
    1. Chromosomes and Gene Expression

    Cancer: Examining the cooperation between extrachromosomal DNA circles

    Jiahui Zhang, Cheng-Zhong Zhang
    In a departure from previous findings, new results suggest that free-floating pieces of DNA which carry additional copies of cancer-driving genes do not tend to cluster or have increased transcription.
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    1. Epidemiology and Global Health
    2. Medicine

    Health: Understanding the links between cardiovascular and psychiatric conditions

    Sonali Amarasekera, Prabhat Jha
    Individuals recently diagnosed with a cardiovascular disease are at higher risk of developing a mental illness, with mortality increasing when both conditions are present.
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    1. Neuroscience

    Computational Neuroscience: A faster way to model neuronal circuitry

    Andrew P Davison, Shailesh Appukuttan
    Artificial neural networks could pave the way for efficiently simulating large-scale models of neuronal networks in the nervous system.
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  3. A pastel blue hand holds a balanced pair of scales across a fractured background; both plates hold the grey silhouette of a scientist, who is either giving a speech (left plate) or looking down a microscope (right plate).

    Equity, Diversity and Inclusion: The hidden toll of community outreach

    Raul A Ramos
    Caught in a system eager for success stories, a PhD student from an underrepresented background learns how to balance his challenges in the lab with his desire to serve his community.
  4. Meta-Research: Systemic racial disparities in funding rates at the National Science Foundation

    Christine Yifeng Chen, Sara S Kahanamoku ... Justin Hosbey
    White principal investigators applying to the National Science Foundation are consistently funded at higher rates than most non-white PIs.
    1. Ecology
    2. Evolutionary Biology

    Evolution: Kin selection spreads

    James P Higham
    By spending more time around infants which physically resemble their own, mandrill mothers may increase how frequently their offspring interact with their paternal half siblings.
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