Junqi Huang, Ting Gang Chew ... Mohan K Balasubramanian
Cytokinetic actomyosin ring disassembly occurs through a novel mechanism in which the increased ring curvature, generated through contraction, itself promotes the disassembly process.
Francesco della Gatta, Francesca Garbarini ... Paola Borroni
An illusion in which individuals feel that their own hand no longer belongs to them may reflect a temporary reduction in the brain’s ability to control the movement of the hand.
LAMP proteins, the major glycoproteins of the lysosome membrane, bind cholesterol directly and specifically, and interact with NPC1 and NPC2 proteins as part of the lysosomal cholesterol export process.
MicroRNA-based direct conversion of human fibroblasts to neurons is applicable to fibroblasts from donors ranging in age from neonatal to centenarian, allowing the generation of neurons that maintain the age-associated signatures of the starting fibroblasts.
Paul Capewell, Christelle Cren-Travaillé ... Annette MacLeod
African trypanosomes residing within the skin of infected humans represent an important yet overlooked transmissible parasite population that may thwart efforts to eliminate African sleeping sickness.
Axonal metabolic flux analysis demonstrates that expression of NMNAT1 blocks axonal degeneration in cultured mouse neurons not by altering NAD+ synthesis, but rather by inhibiting injury-induced, SARM1-dependent NAD+ consumption.
