Microbiology and Infectious Disease

Microbiology and Infectious Disease

eLife reviews research covering virology, bacteriology and mycology. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Structures of LolB bound to LolA or lipoprotein resolve the final steps of bacterial lipoprotein trafficking

    Abigail E Jepson, Elise Kaplan ... Vassilis Koronakis
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Obtaining maximum information from colony counts with REPOP

    Pedro Pessoa, Carol Yunxiao Slayton ... Steve Presse
    Conventional colony counting obscures bacterial population structure by conflating biological heterogeneity with stochastic noise from dilution and plating, which can be separated by explicitly modeling the measurement process.
    1. Microbiology and Infectious Disease

    The structural context of mutations in proteins predicts their effect on antibiotic resistance

    Anna G Green, Mahbuba Tasmin ... Maha Reda Farhat
    Spatial clustering of mutations in Mycobacterium tuberculosis proteins finds proteins that are involved in antibiotic resistance, and predicts which mutations cause resistance.
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    RelB proximity proteomics and CRISPR screening define chromatin regulators of noncanonical NF-κB control of HIV latency and reactivation

    Cameron R Bussey-Sutton, Carley N Gray ... Brian D Strahl
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Tracking maternal proteins uncovers a central role for the residual body in organelle recycling during Toxoplasma gondii replication

    Julia von Knoerzer-Suckow, Parnian Sazegar ... Markus Meissner
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Human CD1c-autoreactive T-cells recognise Mycobacterium tuberculosis-infected antigen-presenting cells and display cytotoxic effector programmes

    Matthew Milton, Sahar H Farag ... Salah Mansour
    CD1c-autoreactive T-cells couple infection-associated lipid recognition with cytotoxic and antimicrobial activity, revealing a previously underappreciated arm of human immunity to tuberculosis.
    1. Microbiology and Infectious Disease

    A novel mechanism for morphological change during bacterial sporulation based on programmed peptidoglycan degradation

    Carlos A Ramírez Carbó, Oihane Irazoki ... Beiyan Nan
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Solid
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Distinct allosteric remodeling of HIV-1 Env dynamics on virions by gp41-directed antibodies reveals two modes of neutralization

    Wang Xu, Narendra Kumar Gonepudi ... Maolin Lu
    Antibodies can target multiple conformational states of the HIV envelope to block viral entry, broadening the mechanisms underlying neutralization.
    1. Microbiology and Infectious Disease

    The type VI secretion system governs strain maintenance in a wild mammalian gut microbiome

    Beth A Shen, Kyle L Asfahl ... Joseph D Mougous
    A type VI secretion system transferred between gut bacteria via a mobile genetic element stabilizes its native host strain, but yields only transient benefits in a new species.
    1. Microbiology and Infectious Disease

    Lactylation of Influenza Virus Polymerase Acidic Protein Promotes Viral Replication and Pathogenicity

    Shaoyu Tu, Yue Du ... Hongbo Zhou
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
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Highlights

    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease
    3. Medicine

    Focus Issue: Trained Immunity

    Edited by Satyajit Rath et al.
    1. Microbiology and Infectious Disease

    Gut Microbiome: Bacteria weigh up costs and benefits of mobile weapons

    Zhao Wang, Yang Fu
    1. Microbiology and Infectious Disease

    Tuberculosis: A surprising new hiding place for a dangerous pathogen

    Sheetal Gandotra, Yogendra Singh

Senior editors

  1. Wendy S Garrett
    Wendy S Garrett
    Harvard T.H. Chan School of Public Health, United States
  2. Diane M Harper
    University of Michigan, United States
  3. Joshua T Schiffer
    Fred Hutchinson Cancer Research Center, United States
  4. See more editors