Kiersten A Henderson, Adam L Hughes, Daniel E Gottschling
Protons are pumped out of mother cells by a protein that accumulates over time and this leads to cellular aging, but this protein is largely absent from daughter cells, which mediates rejuvenation.
Bacterial viruses are an unexpected ‘third party’ that imposes a strong predatory pressure on a bacterial pathogen during the natural course of infection in humans.
A Swedish national cohort study reveals that children with a family history of alcohol use disorders have an increased risk of autism and attention-deficit/hyperactivity disorder.
3-10 weeks old adult-born granule cells provide two temporally overlapping but functionally distinct neuronal cell populations by being sensitive to distinct aspects of their inputs.
Diasynou Fioravante, YunXiang Chu ... Wade G Regehr
Genetic and electrophysiology experiments provide the first direct evidence that protein kinase C is a calcium-sensing protein in post-tetanic potentiation, a form of synaptic plasticity that supports short-term memory.
Maciej M Jankowski, Md Nurul Islam ... Shane M O'Mara
Neurons that provide information about the direction of the head are present in nucleus reuniens and can potentially directly influence spatial processing in the hippocampus.
Well-preserved fossils reveal an extreme morphological specialization of fly larvae, and broaden our understanding of the diversity of ectoparasitism in Mesozoic insects.
Phosphorylation of tyrosine 1 in the carboxy-terminal domain (CTD) of the largest subunit of RNA Polymerase (RNAP) II functions to stabilize this domain, and facilitates turnover of upstream antisense RNAs.
Nicolas Descostes, Martin Heidemann ... Jean-Christophe Andrau
Genome-wide analysis reveals novel functions for a post-translational modification to the carboxy-terminal domain (CTD) of RNA Polymerase II in mammals.