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    1. Genetics and Genomics

    Scientists demonstrate effective strategies for safeguarding CRISPR gene-drive experiments

    New research suggests scientists can now conduct gene-drive research in the lab without the worry of an accidental spread among a natural population.
    1. Cancer Biology

    Scientists identify gene contributing to prostate cancer drug resistance

    The GREB1 gene promotes resistance to prostate cancer treatments, making it a potential target for future therapies.
    1. Cell Biology

    Protein alteration controls cell’s response to stress, immunity and lifespan

    Scientists have discovered a mechanism that switches on stress-response pathways and controls natural immunity and lifespan in worms.
  1. Media coverage: December roundup of eLife papers in the news

    High-profile news coverage that eLife papers generated in December 2018, including Scientific American, Xinhua and Forbes.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Scientists provide new insight on how gene expression is controlled

    New research on transcriptional pausing, which helps control gene expression in cells, will aid our understanding of the enzyme RNA polymerase – a key player in the process and active target for antibacterial drugs.
    1. Evolutionary Biology

    How locusts switch colours in different settings

    A novel mechanism that allows locusts to switch between green and black colouring in response to different environments may also exist in other species.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    New insight on inflammatory regulation could inform future pain drug development

    Researchers have identified a new form of inflammatory regulation that increases our response to painful stimuli.
    1. Evolutionary Biology
    2. Plant Biology

    Fossils suggest flowers originated 50 million years earlier than thought

    The discovery in China of fossil specimens of a flower called Nanjinganthus from the Early Jurassic shakes up widely accepted theories of plant evolution.
  2. eLife editorial leadership expands with expertise in cancer epidemiology, infectious disease and biophysics

    Three Reviewing Editors have been promoted to eLife’s leadership team.
  3. Media coverage: November roundup of eLife papers in the news

    High-profile news coverage that eLife papers generated in November 2018, including Nature, Science and United Press International.