Browse our latest Cancer Biology articles

Genetic analyses reveal how CDX2 and BRAF defects seen in serrated colorectal cancer (CRCs), a poor prognosis CRC subset, cooperate in tumorigenesis in humans and in a mouse cancer model.

Editors' Summary: The results in this Replication Study could not be interpreted.

Editors' Summary: This Replication Study has reproduced important parts of the original paper.

Editors' Summary: The results in this Replication Study could not be interpreted.

Editors' Summary: This Replication Study did not reproduce those experiments in the original paper that it attempted to reproduce.

Editors' Summary: This Replication Study has reproduced important parts of the original paper.

Targeting the transcription factor c-Myc via one of its coactivator proteins is a promising strategy for cancer therapy.

Biological variability has confounded efforts to confirm the role of PREX2 mutations in melanoma.

Experimental efforts to validate the output of a computational model that predicts new uses for existing drugs highlights the inherently complex nature of cancer biology.

The first results from the Reproducibility Project: Cancer Biology suggest that there is scope for improving reproducibility in pre-clinical cancer research.