Browse our latest Cell Biology articles

Cardiovascular disease, the top cause of diabetic deaths, progresses via vascular endothelial dysfunction, with circHMGCS1 and miR4521 highlighted as potential markers for the development of this condition.

Proteins that are low abundant and/or poorly accessible to antibodies can be readily localised with fluorescent streptavidin, when expressed fused to a biotin ligase.

Isotonic treatment limits keratinocyte movement, spatially restricts reactive oxygen species production, and rescues sensory neuron function after thermal injury.

Mouse TRIP13 localizes to synapsed chromosomal axes and thus exhibits mutually exclusive localization with HORMAD1/HORMAD2, providing a cell biological explanation for dissociation of HORMAD1/2 from chromosomal axes upon synapsis.

BoNT intoxication of neurons is revisited using a genome-wide siRNA screen and organelle-specific reporters, suggesting a mechanism of translocation to the cytosol fundamentally different than previously proposed.

An unbiased separation method reveals distinct subpopulations of insulin secretory vesicles that undergo dynamic remodeling upon glucose stimulation.

Regeneration of sensory axons after a burn injury depends on early keratinocyte responses regulated by the wound microenvironment.

The formation of large endolysosomal structures in unfertilized eggs ensures that lysosomes remain dormant before fertilization, and then shift into clean-up mode after the egg-to-embryo transition.