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CERS1 reduction in aging skeletal muscle contributes to impaired muscle function, myogenesis and increases inflammation and fibrosis, highlighting the significance of very long chain ceramides in age-related muscle homeostasis.

Spatiotemporal mapping of a variety of proteins in and around the Golgi apparatus in budding yeast was performed using super-resolution live imaging microscopy and identified the ER-Golgi intermediate compartment that matures into the Golgi.

WRNIP1 has been identified as a pivotal factor in preventing the pathological persistence of R-loop-induced transcription-replication conflicts and the accumulation of DNA damage, thereby ensuring genome integrity.

A brown-to-white adipogenic transdifferentiation process in the periureter region of mouse renal adipose tissue gives rise to a population of cold-inducible adipocytes with a transcriptome distinct from subcutaneous beige adipocytes.

A novel imaging method for measuring myofibril size/number reveals that the radial growth of muscle fibers that occurs in response to increased mechanical loading is largely mediated by myofibrillogenesis.

TGN46 is a cargo receptor, with its luminal domain being necessary and sufficient to load soluble secretory proteins into transport carriers for export out of the trans-Golgi network.

Depletion of VAPA in cancer cells induces defects in actin organization, adhesion dynamics and cell migration, together with a perturbation of phosphoinositide levels at the plasma membrane and a lack of anchoring of ER-PM contact sites to focal adhesions.