Browse our Short Reports

Page 45 of 64
    1. Neuroscience

    Serial, parallel and hierarchical decision making in primates

    Ariel Zylberberg, Jeannette AM Lorteije ... Pieter Roelfsema
    A comparison between hierarchical and flat models of decision-making refutes flat models because they lack flexibility and are not supported by behavioral and neural data.
    1. Neuroscience

    Breaking down hierarchies of decision-making in primates

    Alexandre Hyafil, Rubén Moreno-Bote
    Computational modeling of behavioral and neural data from monkeys points towards a flat decision-making process in which the brain considers all possible final outcomes simultaneously.
    1. Neuroscience

    Activation of the same mGluR5 receptors in the amygdala causes divergent effects on specific versus indiscriminate fear

    Mohammed Mostafizur Rahman, Sonal Kedia ... Sumantra Chattarji
    Activation of the same glutamate receptor in the lateral amygdala gives rise to distinct effects on specific versus indiscriminate fear by modulating intrinsic excitability and synaptic plasticity.
    1. Cancer Biology
    2. Cell Biology

    Caspase-8 contributes to angiogenesis and chemotherapy resistance in glioblastoma

    Giulia Fianco, Maria Patrizia Mongiardi ... Daniela Barilà
    Retention of Caspase-8 confers a selective advantage to glioblastoma and represents a novel therapeutic target.
    1. Epidemiology and Global Health

    Evidence from a natural experiment that malaria parasitemia is pathogenic in retinopathy-negative cerebral malaria

    Dylan S Small, Terrie E Taylor ... Karl B Seydel
    The sickle cell trait strongly protects against not only retinopathy-positive cerebral malaria but also retinopathy-negative cerebral malaria, providing evidence that malarial parasites also contribute to retinopathy-negative cerebral malaria and are not innocent bystanders.
    1. Genetics and Genomics

    Palaeogenomes of Eurasian straight-tusked elephants challenge the current view of elephant evolution

    Matthias Meyer, Eleftheria Palkopoulou ... Michael Hofreiter
    DNA sequences from the Middle Pleistocene reveal that the extinct Eurasian straight-tusked elephants were closely related to today's African forest elephants (Loxodonta cyclotis) in Africa.
    1. Immunology and Inflammation

    The structure of a LAIR1-containing human antibody reveals a novel mechanism of antigen recognition

    Fu-Lien Hsieh, Matthew K Higgins
    The structure of a human antibody in which the variable loops position a human protein LAIR1 for antigen recognition, reveals a novel and indirect mode of antibody function.
    1. Cell Biology
    2. Neuroscience

    A novel ALS-associated variant in UBQLN4 regulates motor axon morphogenesis

    Brittany M Edens, Jianhua Yan ... Yongchao C Ma
    A novel ALS-associated variant in UBQLN4 impairs proteasome function and beta-catenin degradation to drive aberrant axon morphogenesis in motor neurons.
    1. Cell Biology
    2. Plant Biology

    ER assembly of SNARE complexes mediating formation of partitioning membrane in Arabidopsis cytokinesis

    Matthias Karnahl, Misoon Park ... Gerd Jürgens
    SNARE proteins are delivered as complexes already from the endoplasmic reticulum along the secretory pathway to the cell division plane to mediate the formation of the partitioning membrane by vesicle fusion.
    1. Evolutionary Biology

    Homo naledi and Pleistocene hominin evolution in subequatorial Africa

    Lee R Berger, John Hawks ... Eric M Roberts
    A late Middle Pleistocene age for Homo naledi demonstrates a diversity of hominin species in Africa at this critical time in the archaeological record.