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Human cell lines replicate and proliferate without ORC1 or ORC2, two subunits of the replication initiator protein complex ORC, which has till now been considered essential for DNA replication.

The experiences that are most rewarding at the time are not necessarily those that are remembered long-term.

A combination of 7 tesla fMRI and psychophysics revealed the reorganisation of the human somatosensory cortex and changes in tactile perceptual abilities after just 24 hours of altered hand use.

Natural variation for an adaptively important life history trait is largely due to variation at a single, major-effect locus with multiple alleles, demonstrating that not all complex traits are massively polygenic.

BMP guides the evolution of extraembryonic tissue complexity in fly embryos through changes in the control of a positive feedback circuit.

Mineralized placental tissue from Late Byzantine Troy enables the detailed reconstruction of genomes of mixed bacterial species responsible for maternal sepsis in the ancient world.

Replication origins are fundamental organizers and regulators of gene activity through embryonic development.

Neurotransmitter balance in a region in frontal cortex controls how much people use information they have learnt to guide their behaviour.

Current findings help reconcile the contradictory reports regarding the role of infralimbic cortex in the environmental control of appetitive behavior.

Forward genetics and super-resolution microscopy identifies ZitP as a conserved multifunctional regulator that accumulates at both cell extremities in distinct macromolecular structures to perform different functions in the asymmetric model bacterium Caulobacter crescentus.