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Archaea can contain permuted versions of the universal signal recognition particle RNA, which require a moonlighting activity of the tRNA splicing machinery to generate functional circular RNAs.

Female, but not male rats exhibit an active conditioned fear response, which challenges traditional approaches to measuring fear learning exclusively through freezing, and suggests that females use a more diverse set of threat strategies.

A previously suggested expression signature based on thirteen TP53 transcriptional target genes does not predict the response of wild type TP53 tumors to TP53-MDM2 inhibitors.

A synaptic F-actin network tightly controls the flow of synaptic vesicles during exocytosis at the inner hair cell ribbons.

Sleep plays a critical role in the selectivity of memory by promoting the retention of important memories at the expense of less relevant ones.

Artificial light causes changes to gene expression and cellular signaling cascades that coordinate mass spawning events for a species of coral from the Great Barrier Reef.

The role of CaMKII-GluA1 in the cortex in maintaining a given taste memory trace for an aversive association has been elucidated.

Compressive force spectroscopy of single molecules reveals that intra-protein forces underlie the long-distance coordination of structural changes within a cytotoxin during pore formation.

The secreted molecules FAM150A and FAM150B bind to the ALK RTK extracellular domain, potently activating the receptor activation and driving downstream signaling events.

Loss of Kirrel3 selectively reduces DG-GABA mossy fiber filopodia and causes CA3 neuron hyper-activity during brain development.