Browse our Short Reports

Page 60 of 64
    1. Neuroscience

    Hippocampal place cells construct reward related sequences through unexplored space

    H Freyja Ólafsdóttir, Caswell Barry ... Hugo J Spiers
    In anticipation of a reward, hippocampal place cells simulate desired journeys through areas that have been seen, but not explored.
    1. Medicine
    2. Neuroscience

    Neural population dynamics in human motor cortex during movements in people with ALS

    Chethan Pandarinath, Vikash Gilja ... Krishna V Shenoy
    Neural ensemble activity in the human motor cortex contains dynamical structure that is independent of movement parameters and is not well-explained by current models.
    1. Neuroscience

    An excitatory amacrine cell detects object motion and provides feature-selective input to ganglion cells in the mouse retina

    Tahnbee Kim, Florentina Soto, Daniel Kerschensteiner
    The mouse visual system is able to detect small moving objects due to the activity of VG3-amacrine cells, an unusual type of modulatory cell that uses the transmitter glutamate to activate retinal output cells.
    1. Developmental Biology

    The hormonal peptide Elabela guides angioblasts to the midline during vasculogenesis

    Christian SM Helker, Annika Schuermann ... Wiebke Herzog
    Elabela-Apelin receptor signaling is a novel pathway that regulates angioblast migration, instead of the proposed migration regulation through Vascular endothelial growth factor.
    1. Neuroscience

    Projection neurons in Drosophila antennal lobes signal the acceleration of odor concentrations

    Anmo J Kim, Aurel A Lazar, Yevgeniy B Slutskiy
    Neurons in the fruit fly olfactory system respond most strongly to the sudden appearance of an odor, and to odors that are changing rapidly in strength, but are relatively insensitive to the absolute levels of an odor.
    1. Neuroscience

    Loss of the liver X receptor LXRα/β in peripheral sensory neurons modifies energy expenditure

    Virginie Mansuy-Aubert, Laurent Gautron ... Joel K Elmquist
    In sensory neurons, the receptors LXRα and LXRβ sense dietary-derived molecules to regulate whole body energy expenditure, and present a possible target for new anti-obesity agents.
    1. Structural Biology and Molecular Biophysics

    Structure of a type IV pilus machinery in the open and closed state

    Vicki AM Gold, Ralf Salzer ... Werner Kühlbrandt
    Electron cryo-tomography reveals a huge conformational change in the secretin domain of the type IV pilus machinery that occurs when the channel opens for pilus extrusion.
    1. Cell Biology
    2. Neuroscience

    Piezo1 links mechanical forces to red blood cell volume

    Stuart M Cahalan, Viktor Lukacs ... Ardem Patapoutian
    In red blood cells, the Piezo1 protein is responsible for sensing mechanical forces and volume regulation.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Chemical activation of the mechanotransduction channel Piezo1

    Ruhma Syeda, Jie Xu ... Ardem Patapoutian
    A chemical activator of the mechanosensitive Piezo1 ion channel has been identified.
    1. Chromosomes and Gene Expression
    2. Plant Biology

    Local chromatin environment of a Polycomb target gene instructs its own epigenetic inheritance

    Scott Berry, Matthew Hartley ... Martin Howard
    Two copies of a Polycomb target gene in the same cell can be maintained in independently heritable expression states, demonstrating that long-term memory of gene expression is stored locally.