Chethan Pandarinath, Vikash Gilja ... Krishna V Shenoy
Neural ensemble activity in the human motor cortex contains dynamical structure that is independent of movement parameters and is not well-explained by current models.
Tahnbee Kim, Florentina Soto, Daniel Kerschensteiner
The mouse visual system is able to detect small moving objects due to the activity of VG3-amacrine cells, an unusual type of modulatory cell that uses the transmitter glutamate to activate retinal output cells.
Christian SM Helker, Annika Schuermann ... Wiebke Herzog
Elabela-Apelin receptor signaling is a novel pathway that regulates angioblast migration, instead of the proposed migration regulation through Vascular endothelial growth factor.
Neurons in the fruit fly olfactory system respond most strongly to the sudden appearance of an odor, and to odors that are changing rapidly in strength, but are relatively insensitive to the absolute levels of an odor.
Virginie Mansuy-Aubert, Laurent Gautron ... Joel K Elmquist
In sensory neurons, the receptors LXRα and LXRβ sense dietary-derived molecules to regulate whole body energy expenditure, and present a possible target for new anti-obesity agents.
Electron cryo-tomography reveals a huge conformational change in the secretin domain of the type IV pilus machinery that occurs when the channel opens for pilus extrusion.
Two copies of a Polycomb target gene in the same cell can be maintained in independently heritable expression states, demonstrating that long-term memory of gene expression is stored locally.