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Biochemical and genetic characterization of the Cdc6 replication initiator reveals similarities in the helicase loading reaction between bacteria and eukaryotes.

Mammal hearts are unable to replace lost cardiomyocytes, which may be due to the loss of centrosome integrity in these cells after birth.

A shift in antero-posterior positional information may contribute to the fin-to-limb transformation.

An adaptation to extreme winter has involved a shift to autumn temperature monitoring.

Floral scent and nectar are highly variable in natural populations and both traits can influence outcrossing rates differently for different pollinators and increase future herbivory.

Specific elements of the canonical nucleosome are recognized by the multi-component SWR1 chromatin remodeler for ATP-dependent replacement of H2A-H2B dimers with H2A.Z-H2B.

A transgenic small hairpin RNA can provide a viable tool for enhancing resistance to viral infection in livestock and improve animal well-being.

Higher affinity for self-pMHC complexes and broader promiscuity for foreign-pMHC complexes imparts a fitness advantage within the CD4⁺ T cell compartment in older mice.

The first patch-clamp recordings from single cerebellar granule cells during locomotion reveal that the entire step sequence can be predicted from both excitatory synaptic input and output spikes from a single neuron.

A combination of physiological and perceptual experiments show that the responses of rod photoreceptors inhibit those of cones more than vice versa, and reveal both the site of the retinal interaction and the underlying mechanism.