Browse our Short Reports

Page 61 of 65
    1. Chromosomes and Gene Expression
    2. Plant Biology

    Local chromatin environment of a Polycomb target gene instructs its own epigenetic inheritance

    Scott Berry, Matthew Hartley ... Martin Howard
    Two copies of a Polycomb target gene in the same cell can be maintained in independently heritable expression states, demonstrating that long-term memory of gene expression is stored locally.
    1. Neuroscience

    Dysregulated Dscam levels act through Abelson tyrosine kinase to enlarge presynaptic arbors

    Gabriella R Sterne, Jung Hwan Kim, Bing Ye
    Targeting Abelson kinase can be beneficial for treating disorders characterized by dysregulated Down Syndrome Cell Adhesion Molecule signaling.
    1. Biochemistry and Chemical Biology
    2. Ecology

    De novo synthesis of a sunscreen compound in vertebrates

    Andrew R Osborn, Khaled H Almabruk ... Taifo Mahmud
    Many vertebrates are able to synthesize a sunscreen compound de novo and the pathway involved can be used for heterologous production of the compound in yeast.
    1. Cell Biology

    Cellular hallmarks reveal restricted aerobic metabolism at thermal limits

    Aitana Neves, Coralie Busso, Pierre Gönczy
    Cellular hallmarks of thermal limits are evolutionarily conserved in nematodes, and changes in surface to volume ratio reflect restricted aerobic metabolism at these limits.
    1. Chromosomes and Gene Expression

    The transcriptional cofactor TRIM33 prevents apoptosis in B lymphoblastic leukemia by deactivating a single enhancer

    Eric Wang, Shinpei Kawaoka ... Christopher R Vakoc
    TRIM33 performs an essential function in B cell acute lymphoblastic leukemia through an association with a single cis element.
    1. Neuroscience

    fMRI reveals neural activity overlap between adult and infant pain

    Sezgi Goksan, Caroline Hartley ... Rebeccah Slater
    The newborn infant experience of pain closely resembles that observed in adults, suggesting that infants have the sensory and emotional capacity to experience pain.
    1. Cell Biology

    No turnover in lens lipids for the entire human lifespan

    Jessica R Hughes, Vladimir A Levchenko ... Roger JW Truscott
    The carbon in lens membrane lipids correlates to the year of birth of an individual, a phenomenon that is unprecedented in the current body of literature.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Re-visiting the trans insertion model for complexin clamping

    Shyam S Krishnakumar, Feng Li ... Karin M Reinisch
    Biochemical experiments provide support for the trans insertion model for clamping in the regulation of neurotransmitter release by complexin.
    1. Ecology
    2. Evolutionary Biology

    Brood care in a 100-million-year-old scale insect

    Bo Wang, Fangyuan Xia ... Jacek Szwedo
    The discovery of the earliest direct evidence of brood care in insects demonstrates a remarkably conserved egg-brooding reproductive strategy within scale insects in stasis for nearly 100 million years.
    1. Neuroscience

    Corelease of acetylcholine and GABA from cholinergic forebrain neurons

    Arpiar Saunders, Adam J Granger, Bernardo L Sabatini
    Neurons of the cholinergic system, which release the excitatory neurotransmitter acetycholine throughout the cortex, also release the inhibitory transmitter GABA, with potential implications for cognitive function.