Browse our latest Developmental Biology articles

Page 46 of 223
    1. Developmental Biology
    2. Medicine

    Vertical transmission of maternal DNA through extracellular vesicles associates with altered embryo bioenergetics during the periconception period

    David Bolumar, Javier Moncayo-Arlandi ... Felipe Vilella
    In vitro analyses reveal how vertical DNA transmission from the mother to the pre-implantation embryo via endometrial extracellular vesicles can impact embryo bioenergetics.
    1. Developmental Biology
    2. Genetics and Genomics

    Identification of CFAP52 as a novel diagnostic target of male infertility with defects of sperm head-tail connection and flagella development

    Hui-Juan Jin, Tiechao Ruan ... Su-Ren Chen
    CFAP52 is a candidate for genetic diagnosing male infertility with defects of sperm head-tail connection and flagella development.
    1. Developmental Biology

    Development: Investigating the origin of insect metamorphosis

    Xavier Belles
    Experiments exploring the role of juvenile hormone during the life cycle of firebrat insects provide clues about the evolution of metamorphosis.
    Version of Record
    Insight
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Stem Cells: Investigating the impact of cannabis

    Merrick Pierson Smela
    The psychoactive component of cannabis, ∆9-THC, affects cell growth and metabolism in early embryonic cell types in mice.
    Version of Record
    Insight
    1. Developmental Biology
    2. Neuroscience

    Age-associated changes in lineage composition of the enteric nervous system regulate gut health and disease

    Subhash Kulkarni, Monalee Saha ... Pankaj Jay Pasricha
    Mesoderm-derived enteric neurons born in the post-natal vertebrates drive maturation and aging of the enteric nervous system.
    1. Developmental Biology

    Opposing, spatially-determined epigenetic forces impose restrictions on stochastic olfactory receptor choice

    Elizaveta V Bashkirova, Nell Klimpert ... Stavros Lomvardas
    Dorsoventral gradients of transcription factors NFIA, B, and X impose epigenetic and transcriptional spatial restrictions to olfactory receptor expression.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    The reciprocal regulation between mitochondrial-associated membranes and Notch signaling in skeletal muscle atrophy

    Yurika Ito, Mari Yamagata ... Takahiko Sato
    The maintenance of proper mitochondrial-associated endoplasmic reticulum membranes is crucial for preventing skeletal muscle atrophy to interact with the Notch signaling pathway.
    1. Cell Biology
    2. Developmental Biology

    Zn2+ is essential for Ca2+ oscillations in mouse eggs

    Hiroki Akizawa, Emily M Lopes, Rafael A Fissore
    Throughout oocyte maturation, there is a simultaneous elevation in the concentrations of Ca2+ and Zn2+, and the fertilization-induced Ca2+ oscillations cease under Zn2+-deficient conditions, implying an interplay between these ions, potentially at the IP3R1 level that harbors a Zn2+-binding domain.
    1. Cell Biology
    2. Developmental Biology

    Ulk4 promotes Shh signaling by regulating Stk36 ciliary localization and Gli2 phosphorylation

    Mengmeng Zhou, Yuhong Han, Jin Jiang
    Phosphorylation of the pseudokinase Ulk4 by Stk36 promotes primary ciliary tip localization of both proteins to facilitate the phosphorylation and activation of Gli in response to Sonic hedgehog.
    1. Developmental Biology

    Steroidogenesis and androgen/estrogen signaling pathways are altered in in vitro matured testicular tissues of prepubertal mice

    Laura Moutard, Caroline Goudin ... Christine Rondanino
    Although complete mouse in vitro spermatogenesis can be achieved, failure of adult Leydig cell development, with accumulation of progesterone and estradiol, androstenedione deficiency, deregulation of steroidogenic, and steroid target gene expression, were highlighted in organotypic cultures, even with hCG.