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    1. Developmental Biology

    Paternal over- and under-nutrition programme fetal and placental development in a sex-specific manner in mice

    Hannah L Morgan, Nader Eid ... Adam J Watkins
    Poor paternal nutrition at the time of conception shapes post-fertilisation developmental trajectory, fetal growth, and placental dynamics.
    1. Developmental Biology

    Gcn5 – mTORC1 – TFEB signalling axis mediated control of autophagy regulates Drosophila blood cell homeostasis

    Arjun Aji Reeja, Mincy Kunjumon ... Rohan Jayant Khadilkar
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology
    2. Neuroscience

    The microtubule-binding protein EML3 is required for mammalian embryonic growth and cerebral cortical development, and Eml3 null mice are a model of cobblestone brain malformation

    Isabelle Carrier, Eduardo Diez ... Roderick McInnes
    Absence of EML3 in mice leads to delayed embryonic development, small size, perinatal lethality, and the over-migration of neuroblasts due to a defective pial basement membrane.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Arrayed single-gene perturbations identify drivers of human anterior neural tube closure

    Roya E Huang, Giridhar M Anand ... Sharad Ramanathan
    A method for arrayed CRISPRi screening in organoids enables the investigation of morphogenesis in human stem cell-derived tissues, revealing the roles of ZIC2, SOX11, and ZNF521 in neural tube closure.
    1. Cell Biology
    2. Developmental Biology

    Wunen(s) help navigate Primordial Germ Cells by attenuating Hedgehog signaling

    Amrita Roy, Adheena Elsa Roy ... Girish Deshpande
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology
    2. Developmental Biology

    Desert Hedgehog mediates stem Leydig cell differentiation through Ptch2/Gli1/Sf1 signaling axis

    Changle Zhao, Yongxun Chen ... Jing Wei
    Desert Hedgehog signaling promotes stem Leydig cell differentiation through a Ptch2-Gli1-Sf1 regulatory axis in Nile tilapia.
    1. Developmental Biology

    A cell atlas of the developing human outflow tract of the heart and its adult aortic valve derivatives

    Rotem Leshem, Syed Murtuza-Baker ... Nicoletta Bobola
    Transcriptomic profiling of the developing human outflow tract and adult aortic valves reveals that adult valve cells retain distinct embryonic molecular signatures.
    1. Developmental Biology
    2. Neuroscience

    Transcriptional profiling of extraocular motor neurons reveals sim1a as a candidate strabismus-related gene

    Emily Gershowitz, Kyla Rose Hamling ... David Schoppik
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Developmental Biology

    The Par complex regulates apical-basal cell polarity through modulation of FAK signaling homeostasis

    Meiai He, Lining Liang ... Hui Zheng
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology
    2. Genetics and Genomics

    PIK3CA-related overgrowth spectrum (PROS) zebrafish models reveal pan-lineage developmental dysregulation

    Hannah Brunsdon, Nuoya Wang ... E Elizabeth Patton
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Convincing
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