Browse our latest Developmental Biology articles

Page 63 of 223
    1. Cell Biology
    2. Developmental Biology

    Kindlin-2 inhibits TNF/NF-κB-Caspase 8 pathway in hepatocytes to maintain liver development and function

    Huanqing Gao, Yiming Zhong ... Guozhi Xiao
    Biochemical and genetic approaches reveal how the focal adhesion protein kindlin-2 controls the liver development and homeostasis by reducing inflammation.
    1. Cell Biology
    2. Developmental Biology

    Ephrin-B1 regulates the adult diastolic function through a late postnatal maturation of cardiomyocyte surface crests

    Clement Karsenty, Celine Guilbeau-Frugier ... Celine Galés
    Eprhin B1 in the cardiomyocyte regulates the maturation of the adult surface crest architecture and of the diastolic function during a late postnatal stage in rodents.
    1. Developmental Biology
    2. Neuroscience

    Inter-organ Wingless/Ror/Akt signaling regulates nutrient-dependent hyperarborization of somatosensory neurons

    Yasutetsu Kanaoka, Koun Onodera ... Yukako Hattori
    A muscle-derived Wnt signal promotes dendritic branching of somatosensory neurons in response to a concurrent deficiency in vitamins, minerals, and cholesterol.
    1. Developmental Biology
    2. Neuroscience

    Molecular characterization of cell types in the squid Loligo vulgaris

    Jules Duruz, Marta Sprecher ... Simon G Sprecher
    Single-cell transcriptomics correlated with in situ gene expression analysis provide an overview of the diversity and molecular features of cell types in the squid Loligo vulgaris.
    1. Developmental Biology
    2. Genetics and Genomics

    Urotensin II-related peptides, Urp1 and Urp2, control zebrafish spine morphology

    Elizabeth A Bearce, Zoe H Irons ... Daniel T Grimes
    Urp1 and Urp2 peptides, expressed in CSF-contacting neurons in the spinal canal, prevent abnormal curvature of the zebrafish spine.
    1. Developmental Biology
    2. Physics of Living Systems

    On the origin of universal cell shape variability in confluent epithelial monolayers

    Souvik Sadhukhan, Saroj Kumar Nandi
    The nearly universal nature of scaled cell shape variability in an epithelial monolayer is unavoidable, irrespective of health or disease, as it comes from a mathematical property.
    1. Developmental Biology
    2. Evolutionary Biology

    Vocal communication is tied to interpersonal arousal coupling in caregiver-infant dyads

    Sam Wass, Emily Phillips ... Louise Goupil
    Infants' vocalisations are contingent on their own stress physiology, and alter the inter-personal dynamics of how stress states are shared across the infant-caregiver dyad.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    Transcriptional profiling of Hutchinson-Gilford Progeria syndrome fibroblasts reveals deficits in mesenchymal stem cell commitment to differentiation related to early events in endochondral ossification

    Rebeca San Martin, Priyojit Das ... Rachel Patton McCord
    Age-stratified comparisons of gene expression in progeria patient fibroblasts reveals disruption of mesenchymal lineage pathways and points to a deficit in chondrogenic commitment in early development and a depletion of the mesenchymal lineage stem cell pool.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Germline/soma distinction in Drosophila embryos requires regulators of zygotic genome activation

    Megan M Colonnetta, Paul Schedl, Girish Deshpande
    Components of zygotic genome activation, Zelda and CLAMP, contribute to the proper specification of primordial germ cells in Drosophila embryos.
    1. Cell Biology
    2. Developmental Biology

    Aurora A and cortical flows promote polarization and cytokinesis by inducing asymmetric ECT-2 accumulation

    Katrina M Longhini, Michael Glotzer
    Centrosomal Aurora A (AIR-1), together with cortical actomyosin flows, induces polarization of ECT-2, the activator of RHO-1, during polarization and cytokinesis, in order to promote furrow formation.