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Higher body mass index has a wide range of harmful health effects, which sometimes appear to be more pronounced in men, suggesting that higher BMI may be one of the factors contributing to differences in lifespan between men and women.

A pronounced and consistent healthy vaccinee effect has been identified in rigorously conducted vaccine effectiveness studies, specifically within the first 6 months post-vaccination and among older or clinically vulnerable individuals, likely driven by lower vaccination rates among severely ill populations.

A big-data approach shows the effects of menopausal hormone therapy on female brain health might vary depending on the duration of use and history of gynaecological surgery.

Healthy lifestyle changes, particularly improvements in diet and smoking, were inversely related to comprehensive and organ-specific biological aging in Southwest China, highlighting key intervention targets to limit aging.

The observation that an additional vaccine dose provides protection against Omicron variant reinfection in previously vaccinated and infected individuals will help guide future COVID-19 vaccination policies in China and globally.

A panel of serum biomarkers, including dietary and microbial-derived metabolites related to the gut-brain axis, were identified as potential for tracking children at risk of early childhood developmental delays.