Browse our latest Epidemiology and Global Health articles

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    1. Epidemiology and Global Health
    2. Medicine

    Primaquine in glucose-6-phosphate dehydrogenase deficiency: an adaptive pharmacometric assessment of ascending dose regimens in healthy volunteers

    Sasithon Pukrittayakamee, Podjanee Jittamala ... Nicholas J White
    A full radical curative dose of primaquine can be given to fully glucose-6-phosphate dehydrogenase-deficient males safely using an ascending dose regimen.
    1. Epidemiology and Global Health

    Design of the HPV-automated visual evaluation (PAVE) study: Validating a novel cervical screening strategy

    Silvia de Sanjosé, Rebecca B Perkins ... Mark Schiffman
    The PAVE strategy aims to provide a cost-effective, high quality ‘Screen-Triage-Treat’ approach for cervical cancer screening to save many lives.
    1. Cancer Biology
    2. Epidemiology and Global Health

    Identifying metabolic features of colorectal cancer liability using Mendelian randomization

    Caroline Bull, Emma Hazelwood ... Emma E Vincent
    Increased genetic liability to colorectal cancer is associated with altered levels of circulating metabolites, including fatty acids, up to 40 years before average age of diagnosis.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Estimating the contribution of subclinical tuberculosis disease to transmission: An individual patient data analysis from prevalence surveys

    Jon C Emery, Peter J Dodd ... Rein MGJ Houben
    Data analysis and mathematical modelling suggest that subclinical tuberculosis contributes substantially to transmission and needs to be diagnosed and treated for effective progress towards tuberculosis elimination.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Cervical cancer screening improvements with self-sampling during the COVID-19 pandemic

    Miriam Elfström, Penelope Grace Gray, Joakim Dillner
    Improved cervical cancer prevention through greatly increased population coverage by use of self-sampling and HPV screening during the COVID-19 pandemic.
    1. Epidemiology and Global Health
    2. Medicine

    Association between bisphosphonate use and COVID-19 related outcomes

    Jeffrey Thompson, Yidi Wang ... Ulrich H von Andrian
    A claims-based retrospective cohort study shows that patients who used bisphosphonates between 01/01/2019 and 02/29/2020 had dramatically reduced odds of SARS-CoV-2 testing, COVID-19 diagnosis, and COVID-19-related hospitalizations during the initial surge of the COVID-19 pandemic in the US.
    1. Epidemiology and Global Health

    Sleep: Another benefit of regular sleep

    Tianyi Huang
    A large observational study has found that irregular sleep-wake patterns are associated with a higher risk of overall mortality, and also mortality from cancers and cardiovascular disease.
    Version of Record
    Insight
    1. Microbiology and Infectious Disease
    2. Epidemiology and Global Health

    The inter-continental population dynamics of Neisseria gonorrhoeae

    Magnus N Osnes, Ola B Brynildsrud ... Vegard Eldholm
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Epidemiology and Global Health

    Sleep regularity and mortality: a prospective analysis in the UK Biobank

    Lachlan Cribb, Ramon Sha ... Matthew P Pase
    Irregular sleep-wake patterns are associated with higher mortality risk, including mortality due to cancer and cardiovascular disease.
    1. Epidemiology and Global Health

    The impact of COVID-19 on cancer screening and treatment in older adults: The Multiethnic Cohort Study

    Victoria P Mak, Kami White ... Loic Le Marchand
    During the COVID-19 pandemic, cancer-related screening and healthcare practices varied (by age, race/ethnicity, education, and comorbidities), and considering these differences in high-risk individuals' monitoring is important as undiagnosed cases or poor prognosis may increase due to delayed screening/treatment.