Browse our latest Medicine articles

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    1. Epidemiology and Global Health
    2. Medicine

    The impact of measles immunization campaigns in India using a nationally representative sample of 27,000 child deaths

    Benjamin KC Wong, Shaza A Fadel ... Prabhat Jha
    Measles immunization campaigns in India accelerated declines in child measles mortality rates and averted 41,000-56,000 child measles deaths during 2010 to 2013.
    1. Epidemiology and Global Health
    2. Medicine

    Immunization: Reducing measles mortality in India

    Anindya Sekhar Bose
    A large-scale campaign to promote measles vaccinations has substantially reduced the number of children dying from the disease in India.
    Version of Record
    Insight
    1. Medicine

    Meta-Research: Why we need to report more than 'Data were Analyzed by t-tests or ANOVA'

    Tracey L Weissgerber, Oscar Garcia-Valencia ... Stacey J Winham
    Many papers in basic biomedical science do not contain the information that is needed to determine what statistical tests were used and to verify the results of these tests.
    1. Medicine

    Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise

    Matthew Hancock, Anne D Hafstad ... Min Zhang
    Cardiomyocyte Nox4 is a crucial physiological mediator of Nrf2 activation during acute exercise, triggering an adaptive response that preserves redox balance, mitochondrial and cardiac function to support normal physical exercise.
    1. Medicine

    Increase in clinically recorded type 2 diabetes after colectomy

    Anders B Jensen, Thorkild IA Sørensen ... Kristine H Allin
    This nationwide register-based study of diabetes risk after colectomy suggests that the left colon contributes to maintenance of glucose homeostasis.
    1. Medicine
    2. Neuroscience

    Changes in global and thalamic brain connectivity in LSD-induced altered states of consciousness are attributable to the 5-HT2A receptor

    Katrin H Preller, Joshua B Burt ... Alan Anticevic
    LSD induces a pattern of changed global brain connectivity characterized by hypo-connectivity in associative areas and hyper-connectivity across sensory and somatomotor areas that is dependent on the serotonin 2A receptor.
    1. Medicine
    2. Neuroscience

    Prognostication of chronic disorders of consciousness using brain functional networks and clinical characteristics

    Ming Song, Yi Yang ... Tianzi Jiang
    Behavioral, pharmacological, optogenetic, electrophysiological and computational analyses suggest that the anterior dorsal striatum is a causal node in the network responsible for evidence accumulation.
    1. Cancer Biology
    2. Medicine

    Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death

    Haley Hieronymus, Rajmohan Murali ... Charles L Sawyers
    The percentage of a tumor’s genome with alterations in copy number is correlated with increased mortality across a range of tumor types and can be measured using a clinically approved sequencing assay.
    1. Biochemistry and Chemical Biology
    2. Medicine

    Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism

    Erin G Conlon, Delphine Fagegaltier ... James L Manley
    Idiopathic patients along a complex motor neuron disease-dementia spectrum exhibit mRNA splicing changes that are due to multi-protein insolubility.
    1. Medicine

    Research: Adequate statistical power in clinical trials is associated with the combination of a male first author and a female last author

    Willem M Otte, Joeri K Tijdink ... Christiaan H Vinkers
    An analysis of 31,873 clinical trials shows that adequate statistical power was most often present in trials with a male first author and a female last author.