A well-orchestrated machinery for L-leucine uptake is functional in Mycobacterium tuberculosis, which is important for the intracellular survival of the tuberculosis (TB) pathogen.
Juan Bosco Gracia Alvira, Stefanie Migotti ... Christian Schlötterer
Changes in abiotic factors, such as temperature, can affect the host fitness indirectly by modulating subspecies dynamics of key taxa, which are usually overlooked in microbiome research.
Inhibiting the mitochondrial bc1-complex disrupts energy production in mature Toxoplasma gondii bradyzoites, suggesting a metabolic vulnerability in the parasite's chronic, drug-resistant stage.