Browse our latest Microbiology and Infectious Disease articles

The potential of repurposing cipargamin for treating Babesia species offers both theoretical advancements and practical applications in combating parasitic infections.

According to experimental and field observations, stumpy forms appear to be the most adapted forms for African trypanosome transmission from the mammalian host to the tsetse fly in natural conditions.

During cell-to-cell spread, HIV-1 protease activity triggers CARD8 inflammasome activation and IL-1β release from macrophages, which may contribute to inflammation and chronic immune activation.

Caffeic acid phenethyl ester treats Clostridioides difficile infection by neutralizing Clostridioides difficile toxin B and altering the gut microbiota and metabolites.

A mathematical model of pathogen within-host dynamics and experimental validations elucidates the interplay between immune response, damage and pathogen proliferation, highlighting the limitations of current experimental proxies and proposing new methods to better understand host resistance and disease tolerance.

A coiled-coil-based transduction mechanism is identified for a serine/threonine phosphatase that controls a bacterial stress response, suggesting that phosphatases are part of a modularly exchangeable toolkit for bacterial signaling.

M. tuberculosis produces a copper binding diisonitrile chalkophore to maintain the copper-dependent respiratory oxidase during infection, identifying a pathogen strategy that defends oxidative phosphorylation against host attack.

Nervous necrosis virus typically enters host cells via endocytosis, but it can also enter via a process called macropinocytosis.