M Julia Maristany, Anne Aguirre Gonzalez ... Jerelle A Joseph
Phase diagrams for 140 variants of prion-like low-complexity domains are computed to establish scaling laws that quantify the impact of amino acid mutations on the thermodynamic stability of condensates.
David Trombley McSwiggen, Helen Liu ... Hilary P Beck
Single-molecule tracking at scale, analyzing millions of cells and thousands of compounds per day, demonstrates that measuring protein motion provides mechanistic insights relevant to drug discovery.
The composition of nodes that effectively transmit sinusoidal waves in a model network resembling C. elegans' electrical synapses network changes according to the waves' wavenumber.
Fridtjof Brauns, Nikolas H Claussen ... Boris I Shraiman
Active and passive contributions to cell shape change and rearrangements can be distinguished from observed cell geometry, revealing the self-organization mechanisms underlying internally-driven epithelial convergent extension.
The viscous hydraulics of contracting endoplasmic reticulum networks challenge common solute transport theories, suggesting the contraction of peripheral sheets as a plausible driving mechanism.
