Browse our latest Physics of Living Systems articles

Page 54 of 59
    1. Cell Biology
    2. Physics of Living Systems

    Mechanically stimulated ATP release from murine bone cells is regulated by a balance of injury and repair

    Nicholas Mikolajewicz, Elizabeth A Zimmermann ... Svetlana V Komarova
    Bone cells exposed to physiological forces release ATP through repairable membrane injury, generating an intercellular signal that conveys the destructive potential of forces and the adaptive capacity of endangered cells.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    The Ca2+ transient as a feedback sensor controlling cardiomyocyte ionic conductances in mouse populations

    Colin M Rees, Jun-Hai Yang ... Alain Karma
    Feedback sensing of the intracellular calcium concentration suffices to reproduce the diversity of ionic conductances underlying normal cardiac electromechanical function in a genetically diverse population of mice.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Optogenetics enables real-time spatiotemporal control over spiral wave dynamics in an excitable cardiac system

    Rupamanjari Majumder, Iolanda Feola ... Daniel A Pijnappels
    Free optical steering of spiral waves by attraction-based dragging of their cores in optogenetically modified cardiac tissue.
    1. Physics of Living Systems

    Ezrin enrichment on curved membranes requires a specific conformation or interaction with a curvature-sensitive partner

    Feng-Ching Tsai, Aurelie Bertin ... Patricia Bassereau
    Ezrin, an important actin-membrane linker, can zip adjacent membranes, be enriched to positively-curved membranes when phosphorylated and to negatively-curved membranes through a direct interaction with membrane curvature sensor I-BAR domain proteins.
    1. Physics of Living Systems

    Biophysical properties of single rotavirus particles account for the functions of protein shells in a multilayered virus

    Manuel Jiménez-Zaragoza, Marina PL Yubero ... Javier M Rodríguez
    In triple-layered rotavirus particles, strong interaction between the external and middle layers provides high mechanical strength for protection tasks, while weaker interaction between the middle and inner layers favors transcription.
    1. Physics of Living Systems

    Dynamic density shaping of photokinetic E. coli

    Giacomo Frangipane, Dario Dell'Arciprete ... Roberto Di Leonardo
    The concentration of motile bacteria, expressing a light-driven proton pump, can be precisely controlled in space and time by spatially modulating their swimming speeds with a structured light pattern.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Biophysical clocks face a trade-off between internal and external noise resistance

    Weerapat Pittayakanchit, Zhiyue Lu ... Arvind Murugan
    Molecular clocks that are robust to external fluctuations are vulnerable to internal fluctuations and vice versa.
    1. Physics of Living Systems

    Point of View: Are theoretical results ‘Results’?

    Raymond E Goldstein
    There should be a prominent place for theory within biology papers, both as Results in papers that combine experiment and theory, and as Results in theory papers.
    1. Neuroscience
    2. Physics of Living Systems

    Temporal processing and context dependency in Caenorhabditis elegans response to mechanosensation

    Mochi Liu, Anuj K Sharma ... Andrew M Leifer
    Caenorhabditis elegans behavioral response to a mechanosensory signal depends on both the temporal properties of the signal, such as its rate of change, and the animal's current behavior state.
    1. Physics of Living Systems
    2. Computational and Systems Biology

    Global morphogenetic flow is accurately predicted by the spatial distribution of myosin motors

    Sebastian J Streichan, Matthew F Lefebvre ... Boris I Shraiman
    Epithelial tissue remodeling during Drosophila embryonic development is quantitatively described by a simple law relating myosin activity and cell flow.