Browse our latest Stem Cells and Regenerative Medicine articles

Building on previous work (Cai et al., 2014), HIV-derived lentiviral vectors are harnessed to insert user-defined genes into a safe locus in the genome of human stem cells.

Signaling molecules expressed in overlapping body-wide transcriptional gradients determine central axis positional identity in whole-body regeneration.

Upon injury, the regeneration of the adult axolotl brain rebuilds neuronal diversity, but alters the original long-distance circuitry and tissue architecture.

A novel long non-coding RNA targets microRNA miR-34a for epigenetic silencing and initiates asymmetric division of colon cancer stem cells.

A post-translational modification called O-GlcNAcylation modulates the activity of the SOX2 transcription factor in pluripotent stem cells.

Stem cells are found to continually rejuvenate the epidermis of the human parasite Schistosoma mansoni.

Localized silencing of damage-responsive enhancers can block regenerative growth while permitting those same genes to be used for normal development.

The various transposon families of the mammalian genome can adopt different types of repressive chromatin responses upon DNA methylation loss.

Long-term hair follicle stem cells arise by embryonic progenitor cells occupying a niche location that is defined by attenuated Wnt/β-catenin signal.