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    1. Genetics and Genomics
    2. Structural Biology and Molecular Biophysics

    Mutational Scanning: Ion-ing out the genetic variants of Kir2.1

    Braden S Fallon, Justin G English
    Deep mutational scanning provides new insights into how mutations alter the expression and activity of the potassium ion channel Kir2.1, which is associated with many diseases.
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    1. Immunology and Inflammation

    COVID-19: Locked in a pro-inflammatory state

    Chiu Wang Chau, Ryohichi Sugimura
    Macrophages absorbing cells infected with viable SARS-CoV-2 particles fail to transition into an anti-inflammatory state, potentially contributing to a damaging immune reaction linked to severe forms of COVID-19.
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    1. Developmental Biology
    2. Evolutionary Biology

    Tooth Development: What sharks and mammals share

    Sophie Pantalacci
    The tooth shape of sharks and mice are regulated by a similar signaling center despite their teeth having very different geometries.
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    1. Developmental Biology

    Gut Development: A squash and a squeeze

    Danelle Devenport
    Advanced imaging techniques reveal details of the interactions between the two layers of the embryonic midgut that influence its ultimate shape.
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    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Brain Organoids: Getting the right cells

    Bilal Cakir, In-Hyun Park
    Fusing brain organoids with blood vessel organoids leads to the incorporation of non-neural endothelial cells and microglia into the brain organoids.
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    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Natural Killer Cells: Taking on SARS-CoV-2

    Paola Kučan Brlić, Ilija Brizić
    A new study sheds light on how SARS-CoV-2 influences the way natural killer cells can recognize and kill infected cells.
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    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Brain Repair: Gatekeeping astrocyte identity

    Alexis Cooper, Benedikt Berninger
    New findings cast doubt on whether suppressing the RNA-binding protein PTBP1 can force astrocytes to become dopaminergic neurons.
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    1. Neuroscience

    Memory: Associating the old with the new

    Chuqi Liu, Gui Xue
    New memories can strengthen old memories if the recent and past experience contain elements that are semantically related.
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    1. Developmental Biology

    Mitochondria: Powering the formation of alveoli

    Qianjiang Hu, Melanie Königshoff
    Two cell types in the lung need specific numbers and distributions of mitochondria for alveoli to form correctly.
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    1. Evolutionary Biology
    2. Neuroscience

    Pyramidal Neurons: Looking for the origins of axons

    Kathleen S Rockland
    Pyramidal neurons with axons that exit from dendrites rather than the cell body itself are relatively common in non-primates, but rare in monkeys and humans.
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