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    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Defense Proteins: Exposing the invader

    Avraham N Bayer, Fred L Homa
    A restriction factor induced by interferons blocks the replication of herpesviruses by disassembling the capsid proteins surrounding their genome.
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    1. Neuroscience

    Synapses: Dividing communication, at the nanoscale

    Amelia J Ralowicz, Michael B Hoppa
    Fluorescent glutamate sensors shed light on the microscopic organization underlining spontaneous neurotransmission.
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    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Respiro-Fermentation: To breathe or not to breathe?

    Lauren C Radlinski, Andreas J Bäumler
    Listeria monocytogenes uses respiration to sustain a risky fermentative lifestyle during infection.
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    1. Computational and Systems Biology
    2. Evolutionary Biology

    Machine Learning: Lighting up protein design

    Grzegorz Kudla, Marcin Plech
    Using a neural network to predict how green fluorescent proteins respond to genetic mutations illuminates properties that could help design new proteins.
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    1. Immunology and Inflammation

    Autoimmunity: Redoxing PTPN22 activity

    Magdalena Shumanska, Ivan Bogeski
    The oxidative state of a critical cysteine residue determines the enzymatic activity of a phosphatase involved in T-cell immune responses.
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    1. Biochemistry and Chemical Biology

    Genetic Code: Expanding codon size

    Tarana Siddika, Ilka U Heinemann, Patrick O’Donoghue
    Engineering transfer RNAs to read codons consisting of four bases requires changes in tRNA that go beyond the anticodon sequence.
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    1. Genetics and Genomics
    2. Medicine

    Cancer: The aging epigenome

    Brandon L Pierce
    A new approach helps to assess the impact of accelerated epigenetic aging on the risk of cancer.
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    1. Neuroscience

    Learning: The devil is in the task structure

    Orit Nafcha, Uri Hertz
    Conflicting evidence about how the brain processes social and individual learning stems from which type of information is presented as the primary source of knowledge during experiments.
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    1. Neuroscience

    Perception: Where functional MRI stops, metabolism starts

    Polytimi Frangou, William T Clarke
    Combining techniques that track blood oxygenation and biochemicals during neuronal activity reveals how the brain computes perceived and unperceived stimuli.
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    1. Structural Biology and Molecular Biophysics

    Artificial Intelligence: Exploring the conformational diversity of proteins

    Avner Schlessinger, Massimiliano Bonomi
    An artificial intelligence-based method can predict distinct conformational states of membrane transporters and receptors.
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