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    1. Evolutionary Biology

    Super compensatory substitutions restore protein function and flatten fitness landscapes

    Wenhong Jiang, Hengchuang Yin ... Lucas B Carey
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Computational and Systems Biology

    Protein generation with evolutionary diffusion: sequence is all you need

    Sarah Alamdari, Nitya Thakkar ... Kevin K Yang
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    High basal autophagic activity in the brain revealed by systemic quantitative analysis using GFP-LC3-RFP mice

    Yuki Kanda, Tomoya Eguchi ... Noboru Mizushima
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience
    2. Computational and Systems Biology

    Olfactory combinatorial coding supports risk-reward decision making in C. elegans

    Md Zubayer Hossain Saad, William G Ryan ... Bruce A Bamber
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Targeted induction of gut-microbial metabolism acutely affects feeding patterns and clock gene expression in the host

    Giorgia Greter, Claudia Moresi ... Markus Arnoldini
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    Optimising the tilt increment for in situ cryo-electron tomography

    Maarten Willem Tuijtel, Tomáš Majtner ... Martin Beck
    For in situ cryo-electron tomography, smaller tilt increments yield better-aligned tilt-series and higher-quality tomograms, with a 3° increment resulting in optimal subtomogram averaging resolution.
    1. Cell Biology

    Mitochondrial-derived compartments buffer outer membrane protein load during acute mitochondrial adaptation

    Bo J Price, Sai Sangeetha Balasubramaniam, Adam L Hughes
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Distinct nanoscale organizations of mucins and trans-sialidases in Trypanosoma cruzi

    Gonzalo Escalante, Raquel Parada-Puig ... Fernando D Stefani
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    Ferroptosis is executed through caspase-5 cleavage of gasdermin E in ovarian cancer cells

    Mahmuda Akter, Lei Sun ... Shuang Huang
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Macrodomain catalytic activity modulates Chikungunya virus dissemination and transmission potential in Aedes mosquitoes

    Eugenia S Bardossy, Lena Bergmann ... Maria-Carla Saleh
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
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