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    1. Cancer Biology

    Blocking sugar metabolism slows lung tumour growth

    New findings suggest treatments that block two sugar-transporting proteins could help slow the growth of lung tumours.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Virus co-opts immune protein to avoid antiviral defences

    The hepatitis C virus co-opts an immune protein called cyclophilin A to evade antiviral defences, and blocking this protein impairs the virus’s ability to multiply.
  1. eLife and PREreview partner on open discussion and review of preprints

    The two initiatives have come together to engage diverse groups of researchers in the open review of preprints.
    1. Developmental Biology
    2. Genetics and Genomics

    Study identifies network of genes that directs trachea and oesophagus development

    New insight on the genes that allow the wind and food pipe to separate during development may help scientists understand the possible causes of birth defects where the two organs remain joined.
    1. Neuroscience

    Antihistamines and similar drugs could slow down Huntington’s disease

    Controlling dopamine signalling by targeting the histamine receptor has been shown to be a promising strategy for preventing the progression of Huntington’s disease in mice.
    1. Epidemiology and Global Health
    2. Medicine

    Computer modelling predicts where vaccines are needed most

    A new mathematical model can estimate the impact of vaccination strategies against Japanese encephalitis, even in the absence of robust disease surveillance data, identifying priority regions for future vaccinations.
    1. Evolutionary Biology

    Scientists identify ancient origin for key hormone system

    Proteins essential for reproduction, metabolism and immune function trace their evolutionary history all the way back to sea cucumbers.
  2. Media Coverage: May roundup of eLife papers in the news

    High-profile news coverage that eLife papers generated in May 2020, including the Daily Mail, Science and ITV News.
    1. Developmental Biology
    2. Immunology and Inflammation

    Immune cells multiply and diversify in mouse lungs at birth

    A rapid increase in the number and types of immune cells in the lungs of mice after birth may aid development and help protect against infections.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    Genetic tradeoffs do not stop evolution of antibiotic resistance

    New findings suggest bacteria are able to overcome challenging evolutionary compromises at different antibiotic concentrations to develop drug resistance.