Browse our latest Epidemiology and Global Health articles

Page 19 of 52
    1. Epidemiology and Global Health

    Genetically predicted high IGF-1 levels showed protective effects on COVID-19 susceptibility and hospitalization: a Mendelian randomisation study with data from 60 studies across 25 countries

    Xinxuan Li, Yajing Zhou ... Xue Li
    Genetically predicted high insulin-like growth factor levels may decrease the risk of COVID-19 susceptibility and hospitalization.
    1. Epidemiology and Global Health

    Linking rattiness, geography and environmental degradation to spillover Leptospira infections in marginalised urban settings: An eco-epidemiological community-based cohort study in Brazil

    Max T Eyre, Fábio N Souza ... Federico Costa
    While flooding events may drive spillover transmission of Leptospira spp. through dispersal of the bacteria at low elevations, at higher elevations environmental risk is more localised and directly driven by the distribution of local rat reservoir populations.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Constructing an atlas of associations between polygenic scores from across the human phenome and circulating metabolic biomarkers

    Si Fang, Michael V Holmes ... Tom G Richardson
    A comprehensive resource to systematically evaluate the genetically predicted associations between 125 polygenic risk scores and 249 metabolic traits.
    1. Epidemiology and Global Health

    SARS-CoV-2 antibody dynamics in blood donors and COVID-19 epidemiology in eight Brazilian state capitals: A serial cross-sectional study

    Carlos A Prete Jr, Lewis F Buss ... Ester C Sabino
    Blood donor serosurveillance in eight of Brazil’s most populous cities reveals extensive variation of SARS-CoV-2 attack rate across cities, age, and sex groups in December 2020 and increased intrinsic severity of the Gamma variant of concern.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    Estimating the potential to prevent locally acquired HIV infections in a UNAIDS Fast-Track City, Amsterdam

    Alexandra Blenkinsop, Mélodie Monod ... Oliver Ratmann
    Phylogenetic evidence suggests that the majority of HIV infections occurring in the UNAIDS Fast-track city Amsterdam continue to have an Amsterdam resident as source, indicating that the majority of HIV infections in Amsterdam could be prevented through city-level interventions.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    An international observational study to assess the impact of the Omicron variant emergence on the clinical epidemiology of COVID-19 in hospitalised patients

    Bronner P Gonçalves, Matthew Hall ... ISARIC Clinical Characterisation Group
    Combined analyses of publicly available population-level variant data and detailed individual-level clinical data can be used to quantify the clinical impact of new SARS-CoV-2 variants in different settings.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    Transmission Histories: Traversing missing links in the spread of HIV

    Erin Brintnell, Art Poon
    Combining clinical and genetic data can improve the effectiveness of virus tracking with the aim of reducing the number of HIV cases by 2030.
    Version of Record
    Insight
    1. Epidemiology and Global Health

    Trends in female-selective abortion among Asian diasporas in the United States, United Kingdom, Canada and Australia

    Catherine Meh, Prabhat Jha
    While selective abortion of female fetuses is documented within China and India, it is also significant among Asian diaspora in Canada, US, UK and Australia, particularly among Indian diaspora for second or third births following earlier girl birth(s).
    1. Epidemiology and Global Health

    The effect of calcium supplementation in people under 35 years old: A systematic review and meta-analysis of randomized controlled trials

    Yupeng Liu, Siyu Le ... Shuran Wang
    A systematic review and meta-analysis show that calcium supplementation significantly improves bone mass, implying that preventive calcium supplementation in young people (age ≤35 years) may be a shift in the window of intervention for osteoporosis.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Regional importation and asymmetric within-country spread of SARS-CoV-2 variants of concern in the Netherlands

    Alvin X Han, Eva Kozanli ... Chantal Reusken
    Flight restrictions targeted at countries where SARS-CoV-2 variant-of-concern first emerged have limited effectiveness in deterring their introduction into the Netherlands due to the strength of regional travel importation risks in Europe.