Browse our latest Epidemiology and Global Health articles

Page 24 of 52
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Epigenetic scores for the circulating proteome as tools for disease prediction

    Danni A Gadd, Robert F Hillary ... Riccardo E Marioni
    Epigenetic scores for blood protein levels identify those at risk of multiple age-related morbidities, up to 14 years prior to onset.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Biomarkers: Getting closer to the clinic

    Toshiko Tanaka, Luigi Ferrucci
    Associations between plasma protein levels and DNA methylation patterns can be used to predict the onset of age-related chronic disease.
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    1. Epidemiology and Global Health

    Anopheles salivary antigens as serological biomarkers of vector exposure and malaria transmission: A systematic review with multilevel modelling

    Ellen A Kearney, Paul A Agius ... Freya JI Fowkes
    A systematic review with multilevel modelling quantified the positive association between human antibodies to Anopheles salivary proteins with Anopheles-human biting rate and epidemiological measures of malaria transmission, highlighting their potential as a tool to measure vector exposure and malaria transmission.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    DunedinPACE, a DNA methylation biomarker of the pace of aging

    Daniel W Belsky, Avshalom Caspi ... Terrie E Moffitt
    DunedinPACE is a novel DNA methylation biomarker of the pace of biological aging for intervention trials and natural experiment studies investigating how the rate of aging may be changed by behavioral or drug therapy, or by environmental modification.
    1. Epidemiology and Global Health

    Adverse childhood experiences and resilience among adult women: A population-based study

    Hilda Björk Daníelsdóttir, Thor Aspelund ... Unnur Anna Valdimarsdóttir
    Cumulative exposure to adverse childhood experiences is associated with lower adult resilience among women in a dose-dependent manner, independent of adult socioeconomic factors and social support, indicating that adult female resilience is consolidated in early life.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    Primate malarias as a model for cross-species parasite transmission

    Marina Voinson, Charles L Nunn, Amy Goldberg
    Ecological and evolutionary perspectives are critical to understand, predict, prevent, and treat malaria parasites that may spread to humans from our close primate relatives.
    1. Epidemiology and Global Health

    Risk factors relate to the variability of health outcomes as well as the mean: A GAMLSS tutorial

    David Bann, Liam Wright, Tim J Cole
    We provide a tutorial to use GAMLSS, applied using cohort data to study how risk factors may influence both the mean and variability of body mass index and mental health.
    1. Epidemiology and Global Health
    2. Medicine

    Ten months of temporal variation in the clinical journey of hospitalised patients with COVID-19: An observational cohort

    ISARIC Clinical Characterisation Group, Matthew D Hall ... Piero L Olliaro
    Patient outcomes, and the time spent by patients during hospital admission, showed considerable variation over the first year of the COVID-19 pandemic.
    1. Epidemiology and Global Health
    2. Medicine

    Development, validation, and application of a machine learning model to estimate salt consumption in 54 countries

    Wilmer Cristobal Guzman-Vilca, Manuel Castillo-Cara, Rodrigo M Carrillo-Larco
    A machine learning model could accurately estimate daily salt consumption in the general population and can be applied to countries lacking urine sample to compute the mean salt consumption at the population level.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation

    Susan Martin, Jessica Tyrrell ... Hanieh Yaghootkar
    Using genetics, it is possible to uncouple higher adiposity from its adverse metabolic effects and show that some obesity-associated conditions may benefit from treating the metabolic effects alone, whilst others may benefit more from weight loss.