Browse our latest Epidemiology and Global Health articles

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    1. Medicine
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    3. Epidemiology and Global Health
    4. Immunology and Inflammation
    Covid-19. Translational and Clinical Research

    Infectious Diseases: A Collection of Translational and Clinical Research Articles

    Edited by Bavesh Kana et al.
    eLife has published articles on a wide range of infectious diseases, including COVID-19, influenza, tuberculosis, HIV/AIDS, malaria and typhoid fever.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    The repurposing of Tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively drug-resistant Shigella spp

    Elena Fernández Álvaro, Phat Voong Vinh ... Stephen Baker
    The oral carbapenem 'Tebipenem' has high level antibacterial activity against highly drug-resistant Shigella, and its mode of action and pharmacokinetics make it suitable for the treatment of severe diarrhoea caused by highly drug-resistant bacteria.
    1. Cancer Biology
    2. Epidemiology and Global Health

    Effect of cancer on outcome of COVID-19 patients: a systematic review and meta-analysis of studies of unvaccinated patients

    Giulia Di Felice, Giovanni Visci ... Paolo Boffetta
    A twofold increased risk of adverse outcomes (mortality, ICU admission, and severity of COVID-19) has been demonstrated in unvaccinated COVID-19 patients with cancer compared to COVID-19 patients without cancer.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Taller height and risk of coronary heart disease and cancer: A within-sibship Mendelian randomization study

    Laurence J Howe, Ben Brumpton ... Neil M Davies
    Genetic data from siblings provides strong evidence that taller height increases the risk of cancers but lowers the risk of coronary disease.
    1. Epidemiology and Global Health
    2. Medicine

    Ontogeny of circulating lipid metabolism in pregnancy and early childhood – a longitudinal population study

    Satvika Burugupalli, Adam Alexander T Smith ... Barwon Infant Study Investigator team
    Plasma lipidomic profiling in pregnancy, infancy and early childhood provides a framework to define the relationship between lipid metabolism and health outcomes in early childhood.
    1. Epidemiology and Global Health
    2. Medicine

    Risk of heart disease following treatment for breast cancer – results from a population-based cohort study

    Haomin Yang, Nirmala Bhoo-Pathy ... Kamila Czene
    Long-term increased risks of arrhythmia and heart failure were found in breast cancer patients, while systemic adjuvant therapies including trastuzumab and anthracyclines were associated with the increased risk of heart failure.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Identification of autosomal cis expression quantitative trait methylation (cis eQTMs) in children’s blood

    Carlos Ruiz-Arenas, Carles Hernandez-Ferrer ... Mariona Bustamante
    A catalogue of associations between DNA methylation and gene expression in children will improve the interpretation of Epigenome-Wide Association Studies.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Environmentally sensitive hotspots in the methylome of the early human embryo

    Matt J Silver, Ayden Saffari ... Andrew M Prentice
    259 CpGs associated with season of conception in rural Gambians constitute a valuable resource for investigating epigenetic mechanisms linking early exposures to lifelong health and disease.
    1. Epidemiology and Global Health
    2. Medicine

    External validation of a mobile clinical decision support system for diarrhea etiology prediction in children: A multicenter study in Bangladesh and Mali

    Stephanie Chow Garbern, Eric J Nelson ... Daniel T Leung
    A smartphone app incorporating clinical prediction models using patient-specific and location-specific data sources in a modular approach could predict viral-only etiology of diarrhea in children under five in Bangladesh and Mali.
    1. Epidemiology and Global Health
    2. Medicine

    Investigating phenotypes of pulmonary COVID-19 recovery: A longitudinal observational prospective multicenter trial

    Thomas Sonnweber, Piotr Tymoszuk ... Judith Löffler-Ragg
    Protracted systemic and microvascular inflammation, as well as high anti-SARS-CoV-2 antibody levels, is associated with a high risk of persistent structural and functional lung deficits 6 months after COVID-19.