Pengxing Cao, Katharine A Collins ... James M McCaw
A mathematical model of blood-stage infection with Plasmodium falciparum malaria capturing the sexual stage of the parasite life-cycle is validated against human data, providing new insight into human-to-mosquito transmission.
Kimberly M Fornace, Neal Alexander ... Chris Drakeley
Local human movement into mosquito habitats around forest edges intensifies interactions between pathogens, insects and people, increasing exposure risks to the zoonotic malaria Plasmodium knowlesi in Malaysian Borneo.
Nationally-representative verbal autopsies can be linked to seasonal patterns, clinical syndromes, and climate regions to describe novel insights regarding the microbiologic etiologies of childhood pneumonia and diarrhea in India.
The structure and composition of the elusive vertex complex in Tectiviridae is finally revealed and the newly reported protein conformations help to maintain the capsid architecture.
Benjamin F Arnold, Diana L Martin ... Jeffrey W Priest
Among children in low-resource settings, diverse enteropathogens share common, population-level antibody dynamics, which creates a new opportunity to estimate transmission through serologic surveillance.
Variation in the rate of mixed infections by malaria parasites and the relatedness structure among infecting strains reveals diversity in local epidemiological processes.
Isabel Rodriguez-Barraquer, Henrik Salje, Derek A Cummings
Age-specific incidence data, combined with mechanistic models of immunity, provides a unique opportunity to characterize disease transmission of dengue and other immunizing diseases at high temporal and spatial resolution.