Browse our latest Immunology and Inflammation articles

Therapeutic hypothermia mitigates ventilator-induced lung injury by suppressing macrophage-derived IL-1β release, thereby reducing neutrophil extracellular trap formation, vascular leakage, and hypoxemia in a two-hit acute lung injury model.

Trained immunity is a form of innate immune cell memory that is being developed as a novel immunotherapeutic approach for cancer treatment.

During cell-to-cell spread, HIV-1 protease activity triggers CARD8 inflammasome activation and IL-1β release from macrophages, which may contribute to inflammation and chronic immune activation.

The interferon-induced GTPase GVIN1 prevents bacteria from spreading among cells by coating them and rendering them immobile.

Combining phylogenetic analyses and functional assays to study the receptor interacting protein kinase family reveals conserved and non-conserved functions in immune signaling across vertebrates.

IFN-β-induced WTAP phase transition bridges STAT1 and MTC, which orchestrates m⁶A dynamics on ISG mRNAs to suppress excessive immune response and sustain immune homeostasis.

Pf-GARP antigen seems to be a better malaria vaccine candidate compared to PfSEA-1A, as it triggered the activation of cTFH17, involved in the maintenance of memory antibody responses in adults.

Co-culture between donor-derived iPSC-induced macrophages and forebrain organoids revealed microglial impairment leading to the degenerative neuro-environment in HDLS.