Browse our latest Immunology and Inflammation articles

Early suPAR-guided anakinra decreases the risk for severe respiratory failure in SARS-CoV-2 pneumonia and restores the pro-/anti-inflammatory balance.

Simultaneous multimodal measurement of chromatin accessibility, gene expression, and protein expression provides a unified view of the molecular underpinnings of immune cell state in health and disease.

Early postmortem autopsy of COVID-19 patients shows high viral loads and damage of the lung, although extrapulmonary cells demonstrate no injury, they contribute to inflammation, hyper-coagulation, and multiple organ dysfunction.

Wnt signaling is revealed to be a regulator of macrophage inflammation-resolving state in atherosclerosis through a PGE2-mediated pathway.

Inducing neuronal mitochondrial activity during central nervous system inflammation counteracts inflammation-induced neuronal electron transport chain deficiency and calcium toxicity, thereby protecting against neuronal loss in a multiple sclerosis mouse model.

COVID-19 survivors, who are at risk for vascular complications, would benefit from close monitoring and preventive therapy.

Malaria remodels the spleen to imprint tolerance and reduce pathology in subsequent infections.

Structural and functional analysis of a new class of low-molecular-weight antibody fragments, derived from bovine immunoglobulins, reveals their therapeutic potential against C5, a target for refractory inflammatory diseases.

Stratification of COVID19 patients using quantitative metrics of seroconversion reveals distinct pathophysiological stages after SARS-CoV-2 infection, including key differences in immune cell types, inflammatory makers, and markers of organ function.

In vivo time lapse imaging reveals that microglial trogocytosis of presynaptic elements is regulated by the complement system which controls axon morphogenesis in the developing brain.