Browse our latest Medicine articles

Page 59 of 65
    1. Medicine

    High-phytate/low-calcium diet is a risk factor for crystal nephropathies, renal phosphate wasting, and bone loss

    Ok-Hee Kim, Carmen J Booth ... Byung-Chul Oh
    A high-phytate-low Ca2+ diet causes crystal nephropathies, renal phosphate wasting, and bone disease in rats, whereas high Ca2+ intake ameliorates the detrimental effects of a high-phytate diet.
    1. Medicine

    A synthetic dataset primer for the biobehavioural sciences to promote reproducibility and hypothesis generation

    Daniel S Quintana
    Sharing synthetic datasets that mimic original datasets that could not otherwise be made publicly available can help ensure reproducibility and facilitate data exploration while maintaining participant privacy.
    1. Epidemiology and Global Health
    2. Medicine

    Estimated effectiveness of symptom and risk screening to prevent the spread of COVID-19

    Katelyn Gostic, Ana CR Gomez ... James O Lloyd-Smith
    Even in the best-case scenario, screening for COVID-19 misses well over half of infected travellers.
    1. Medicine

    Intermittent hypoxia mediated by TSP1 dependent on STAT3 induces cardiac fibroblast activation and cardiac fibrosis

    Qiankun Bao, Bangying Zhang ... Guangping Li
    Targeting STAT3 provides a potential therapeutic strategy for obstructive sleep apnea-related fibrotic heart disease mediated by TSP1.
    1. Medicine

    Ankyrin-G mediates targeting of both Na+ and KATP channels to the rat cardiac intercalated disc

    Hua-Qian Yang, Marta Pérez-Hernández ... William A Coetzee
    The functional interaction of Na+ and KATP channels at the intercalated disk of cardiomyocytes depends on Ankyrin G and is clinically relevant since KATP channel mutations affect Na+ channel expression.
    1. Medicine
    2. Neuroscience

    Disease-modifying effects of natural Δ9-tetrahydrocannabinol in endometriosis-associated pain

    Alejandra Escudero-Lara, Josep Argerich ... Rafael Maldonado
    A mouse model of endometriosis reveals that moderate doses of Δ9-tetrahydrocannabinol produce clear regression of ectopic endometrial growths, pronounced alleviation of pelvic pain and unexpected memory improvements.
    1. Medicine

    Decreasing human body temperature in the United States since the Industrial Revolution

    Myroslava Protsiv, Catherine Ley ... Julie Parsonnet
    Since the Industrial Revolution, normal body temperature in both men and women has decreased monotonically by 0.03°C per birth decade.
    1. Computational and Systems Biology
    2. Medicine

    Single-cell modeling of routine clinical blood tests reveals transient dynamics of human response to blood loss

    Anwesha Chaudhury, Geoff D Miller ... John M Higgins
    Unsteady state modeling of blood cell populations reveals that blood loss triggers a cellular clearance delay and a cellular production increase, and modeling provides earlier detection and individualized patient characterization.
    1. Epidemiology and Global Health
    2. Medicine

    Risk factors for asthma among schoolchildren who participated in a case-control study in urban Uganda

    Harriet Mpairwe, Milly Namutebi ... Alison M Elliott
    Asthma risk among schoolchildren increases depending on area of residence in early life, from rural to town to city, and this risk increases further with other known risk factors.
    1. Cancer Biology
    2. Medicine

    Improving drug discovery using image-based multiparametric analysis of the epigenetic landscape

    Chen Farhy, Santosh Hariharan ... Alexey V Terskikh
    A novel phenotypic screening platform based on immunofluorescent imaging of histone modifications enables accurate identification of cell fates and environmental perturbations.