Browse our latest Microbiology and Infectious Disease articles

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    1. Microbiology and Infectious Disease

    Interferon receptor-deficient mice are susceptible to eschar-associated rickettsiosis

    Thomas P Burke, Patrik Engström ... Matthew D Welch
    Type I interferon and interferon-γ signaling redundantly protects mice from the tick-borne pathogen Rickettsia parkeri in the skin, and interferon receptor-deficient mice are a tractable model for investigating rickettsiosis.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Ancient Viruses: How infectious diseases arrived in the colonial Americas

    Ville N Pimenoff, Charlotte J Houldcroft
    Analysis of viral DNA from human remains suggests that the transatlantic slave trade may have introduced new pathogens that contributed to the devastating disease outbreaks in colonial Mexico.
    Version of Record
    Insight
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Ancient viral genomes reveal introduction of human pathogenic viruses into Mexico during the transatlantic slave trade

    Axel A Guzmán-Solís, Viridiana Villa-Islas ... María C Ávila Arcos
    The characterization of ancient B19V and HBV genotype A4 viruses circulating during Colonial epidemics provides new insights into the pathogens that were introduced to the Americas after the European colonization.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    The roles of history, chance, and natural selection in the evolution of antibiotic resistance

    Alfonso Santos-Lopez, Christopher W Marshall ... Vaughn S Cooper
    Selection imposed by antibiotics may dominate evolutionary forces acting on opportunistic pathogens like Acinetobacter baumannii, yet chance effects and a prior history in biofilm may constrain resistance and impose collateral sensitivities.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Uniparental nuclear inheritance following bisexual mating in fungi

    Vikas Yadav, Sheng Sun, Joseph Heitman
    Discovery of a novel mode of sexual reproduction, termed pseudosexual reproduction, in fungi where both parents are required for mating but only one contributes to the meiotic progeny, similar to hybridogenesis in animals.
    1. Ecology
    2. Microbiology and Infectious Disease

    Niche partitioning facilitates coexistence of closely related honey bee gut bacteria

    Silvia Brochet, Andrew Quinn ... Philipp Engel
    Experiments in gnotobiotic bees and culture tubes can recapitulate gut microbiota coexistence patterns observed in nature.
    1. Ecology
    2. Microbiology and Infectious Disease

    Microbiome: What can we learn from honey bees?

    Julia A Schwartzman
    The Western honey bee provides a model system for studying how closely related species of bacteria are able to coexist in a single community.
    Version of Record
    Insight
    1. Microbiology and Infectious Disease

    Co-circulation of multiple influenza A reassortants in swine harboring genes from seasonal human and swine influenza viruses

    Pia Ryt-Hansen, Jesper Schak Krog ... Lars Erik Larsen
    The abundance and complex genetic diversity of swIAV were documented and the zoonotic potential evaluated.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    Host-associated microbe PCR (hamPCR) enables convenient measurement of both microbial load and community composition

    Derek S Lundberg, Pratchaya Pramoj Na Ayutthaya ... Detlef Weigel
    hamPCR is a cost-effective and transformative amplicon sequencing strategy to describe microbiota composition and measure its overall abundance, applicable to all samples in which host and microbial DNA are co-extracted.
    1. Microbiology and Infectious Disease

    Loss of N1-methylation of G37 in tRNA induces ribosome stalling and reprograms gene expression

    Isao Masuda, Jae-Yeon Hwang ... Ya-Ming Hou
    Biochemical and genome-wide analysis demonstrates that m1G37 is important for tRNA aminoacylation and for the entire elongation cycle of protein synthesis.