Irina Kalita, Ira Alexandra Iosub ... Meriem El Karoui
Single-molecule mRNA and protein quantification, combined with stochastic modelling, uncover a post-transcriptional regulatory mechanism that controls the expression of the extremely low-abundance DNA double-strand break repair enzyme RecBCD.
Giorgio Nicoletti, Matteo Bruzzone ... Daniel Maria Busiello
The onset of habituation phenomena enables accurate processing of external stimuli when biological systems adapt their parameters to balance dissipation and the information between input and response.
Reaction-diffusion network modeling unveils general design principles that both stabilize cell polarization patterns and enable tunable interface localization, reconciling extensive experimental observations and deepening the understanding of asymmetric cell division.
Gliding multicellular cyanobacteria results from cellular coordination, the loss of which results in the collapse of orderly back-and-forth movement of filaments and in filament buckling.
Animals may learn to locate preys effectively by memorizing short excerpts of their scent trace, which duration is dictated by the sparse nature of turbulent odor plumes.
Theoretical modeling uncovers an unusual acceleration in microbial growth following osmotic shock, driven by the coordinated regulation of osmolyte production and cell-wall synthesis.
A simple mathematical model, incorporating reversible deactivation of β-cells, can potentially explain the rapid onset and remission of a diabetes subtype, ketosis-prone diabetes.
Saloni Goyal, Divya Rajendran ... Athi N Naganathan
Polyphosphate, a universal stress response regulator, binds distinctively to different starting ensembles of the same protein leading to either condensates or aggregates that in turn can solubilize or further aggregate, showcasing their ability to finely control the assembly process.
Magnetic resonance imaging, through its sensitivity to ionic environments that modulate membrane potential, enables noninvasive assessment of biological systems.
