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A correlation between the periplasmic embellishment of the flagellar motor and its stator system type is described, motors with dual H+-dependent stator systems have one periplasmic ring formed by MotY.

Hantaan virus nucleocapsid cryo-EM structure determined at 3.3 Å resolution reveals how nucleoproteins assemble into a metastable helix containing a continuous RNA-binding groove compatible with genome encapsidation and compaction.

Genes drives utilizing synthetic target sites and the split-Cas9 system have similar performance to standard drives.

Antibody paratopes can be added to the human repertoire by CRISPR-Cas9 editing of B lymphocytes using a strategy that allows for hypermutation and class switching of resulting B cell receptors.

Top-bottom patterning of leaves is not specified by an asymmetry in the distribution of the plant hormone auxin, in contrast to a previous proposal.

Training-induced perceptual gain in the discrimination between odor enantiomers is nostril-specific and structure-based, indicating that early olfactory processing of the chemical features of unirhinal input remains plastic in human adults.

During embryonic development, tissue stiffness, which provides an important signal to motile cells, changes locally within tens of minutes in a well-controlled manner.

Zebrafish insulin mutants serve as an innovative platform to identify novel mechanisms regulating glucose homeostasis.

Proteins can fold deeper inside ribosomes with an enlarged exit tunnel.

Activation of the Estrogen Receptor by estra-2-diol results in sustained binding and the previously described cyclical response kinetics are likely an artefact of observing a highly variable process without replicates.