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    1. Developmental Biology
    2. Neuroscience

    The microtubule-binding protein EML3 is required for mammalian embryonic growth and cerebral cortical development, and Eml3 null mice are a model of cobblestone brain malformation

    Isabelle Carrier, Eduardo Diez ... Roderick McInnes
    Absence of EML3 in mice leads to delayed embryonic development, small size, perinatal lethality, and the over-migration of neuroblasts due to a defective pial basement membrane.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Inferring variant-specific effective reproduction numbers from combined case and sequencing data

    Marlin D Figgins, Trevor Bedford
    Integrating case counts with genomic sequences quantifies real-time transmission advantages of viral variants.
    1. Evolutionary Biology
    2. Plant Biology

    Correction: Asymmetrical diversification of the receptor-ligand interaction controlling self-incompatibility in Arabidopsis

    Maxime Chantreau, Céline Poux ... Vincent Castric
    1. Medicine

    Correction: Intermittent fasting promotes type 3 innate lymphoid cells secreting IL-22 contributing to the beigeing of white adipose tissue

    Hong Chen, Lijun Sun ... Yue Yin
    1. Neuroscience

    Whisker-based pre-neuronal and peripheral encoding of surface stickiness

    Isis S Wyche, Michaela A O’Neil, Daniel H O’Connor
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Solid
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Cell cycle dependent variation in endocytosis drives phenotypic diversity in M. tuberculosis

    Neeraja Subhash, Sandhya Krishnan Radhakrishnan ... Varadharajan Sundaramurthy
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Human and mouse cerebellar inhibitory circuits in dystonic crisis and their modulation with therapeutic stimulation

    Alejandro G Rey Hipolito, Michael P Dew ... Roy V Sillitoe
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Medicine

    Single-cell transcriptome-wide Mendelian randomization and colocalization analyses reveal immune-cell-specific mechanisms and actionable drug targets in prostate cancer

    Yanggang Hong, Yi Wang ... Jiajun Li
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    Celldetective, an AI-enhanced image analysis tool for unraveling dynamic cell interactions

    Rémy Torro, Beatriz Díaz-Bello ... Laurent Limozin
    Celldetective is an open-source software integrating segmentation, tracking, and event detection to perform high-throughput end-to-end study of dynamic cell interactions, without requiring coding skills, demonstrated on microscopy immunological assays.
    1. Neuroscience

    Medial prefrontal cortex encodes but is not required to generate goal-directed actions under threat

    Muhammad S Sajid, Ji Zhou, Manuel A Castro-Alamancos
    Medial prefrontal cortex activity is not required for learning or execution of adaptive avoidance behavior, despite encoding select task features.
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