Browse our latest Chromosomes and Gene Expression articles

Page 61 of 124
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Nanopore direct RNA sequencing maps the complexity of Arabidopsis mRNA processing and m6A modification

    Matthew T Parker, Katarzyna Knop ... Gordon G Simpson
    Sequencing mRNA directly with nanopores can reveal the authentic combinations of multiple mRNA processing events in full-length mRNA molecules in addition to identifying base modifications.
    1. Chromosomes and Gene Expression

    The CDK Pef1 and protein phosphatase 4 oppose each other for regulating cohesin binding to fission yeast chromosomes

    Adrien Birot, Marta Tormos-Pérez ... Jean-Paul Javerzat
    Cohesin loader activity is regulated by phosphorylation of its cohesin substrate.
    1. Chromosomes and Gene Expression

    The Fml1-MHF complex suppresses inter-fork strand annealing in fission yeast

    Io Nam Wong, Jacqueline PS Neo ... Matthew C Whitby
    Genomic deletions formed from inter-fork strand annealing associated with a collapsed replication fork are suppressed by the FANCM-related DNA helicase Fml1 in conjunction with its partner proteins Mhf1 and Mhf2.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Vasohibin1, a new mouse cardiomyocyte IRES trans-acting factor that regulates translation in early hypoxia

    Fransky Hantelys, Anne-Claire Godet ... Anne-Catherine Prats
    In mouse cardiomyocytes, (lymph)angiogenic growth factors are induced during early hypoxia by a translational mechanism involving a new IRES trans-acting factor, vasohibin-1.
    1. Chromosomes and Gene Expression

    GC content shapes mRNA storage and decay in human cells

    Maïté Courel, Yves Clément ... Dominique Weil
    The GC content of human mRNAs is key to P-body localization and protein yield, and has a major impact on their post-transcriptional control.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Distinct roles for S. cerevisiae H2A copies in recombination and repeat stability, with a role for H2A.1 threonine 126

    Nealia CM House, Erica J Polleys ... Catherine H Freudenreich
    Despite differing by only one amino acid in the C-terminal tail, copy 1 of yeast histone 2A has a repair-specific role not shared by copy 2.
    1. Chromosomes and Gene Expression

    Crl activates transcription by stabilizing active conformation of the master stress transcription initiation factor

    Juncao Xu, Kaijie Cui ... Yu Zhang
    The cryo-EM structure of Escherichia coli Crl–TAC reveals the mechanism of DNA-contact-independent transcription activation.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Har-P, a short P-element variant, weaponizes P-transposase to severely impair Drosophila development

    Satyam P Srivastav, Reazur Rahman ... Nelson C Lau
    A female fertility syndrome in Drosophila called gonadal dysgenesis is caused by the P-transposase actively mobilizing a very short P-element variant that has been named the Har-P.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle

    Elias T Friman, Cédric Deluz ... David M Suter
    OCT4 and SOX2 display partially independent activity to regulate chromatin accessibility, and highly dynamic activity of OCT4 is required throughout the cell cycle to maintain pluripotency enhancer accessibility.
    1. Chromosomes and Gene Expression

    An mRNA-binding channel in the ES6S region of the translation 48S-PIC promotes RNA unwinding and scanning

    Irene Díaz-López, René Toribio ... Iván Ventoso
    The ES6S region of the small subunit ribosome makes a place for the threading and secondary structure unwinding of mRNA, which regulates genome-wide translation.