Browse our latest Developmental Biology articles

Page 49 of 223
    1. Developmental Biology

    A scalable and tunable platform for functional interrogation of peptide hormones in fish

    Eitan Moses, Roman Franek, Itamar Harel
    A novel in vivo strategy for reversible, multiplexed control of circulating hormone expression levels, achieved by combining genome-editing and intramuscular electroporation of fluorescently tagged hormones in the naturally short-lived turquoise killifish.
    1. Developmental Biology

    C-type natriuretic peptide improves maternally aged oocytes quality by inhibiting excessive PINK1/Parkin-mediated mitophagy

    Hui Zhang, Chan Li ... Baohua Ma
    In vitro and in vivo data show that C-natriuretic peptide is significant for increasing mitochondrial bioenergetics by cAMP-PKA pathway and improving cytoplasmic and nuclear maturation of maternally aged oocyte.
    1. Computational and Systems Biology
    2. Developmental Biology

    A comprehensive model of Drosophila epithelium reveals the role of embryo geometry and cell topology in mechanical responses

    Mohamad Ibrahim Cheikh, Joel Tchoufag ... Konstantin Doubrovinski
    Direct mechanical microcantilever-based measurements establish key material parameters describing mechanical response of the early Drosophila embryonic epithelium.
    1. Developmental Biology
    2. Genetics and Genomics

    DMRT1 is a testis-determining gene in rabbits and is also essential for female fertility

    Emilie Dujardin, Marjolaine André ... Maëlle Pannetier
    The absence of DMRT1 induces a male-to-female sex reversal in XY rabbits and complete infertility in both sexes.
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    Research Article
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    1. Developmental Biology
    2. Genetics and Genomics

    Microhomology-mediated circular DNA formation from oligonucleosomal fragments during spermatogenesis

    Jun Hu, Zhe Zhang ... Chao Liu
    Germline extrachromosomal circular DNAs are mainly formed by microhomology-mediated ligation of nucleosome-protected fragments and barely contribute to de novo genomic deletions at meiotic recombination hotspots.
    1. Developmental Biology

    Chromatin and gene expression changes during female Drosophila germline stem cell development illuminate the biology of highly potent stem cells

    Liang-Yu Pang, Steven DeLuca ... Allan C Spradling
    Chromatin changes downstream from Drosophila germline stem cells and fertilized zygotes alter how transposable element activity and gene expression are controlled to facilitate differentiation.
    1. Developmental Biology
    2. Evolutionary Biology

    Hybridization led to a rewired pluripotency network in the allotetraploid Xenopus laevis

    Wesley A Phelps, Matthew D Hurton ... Miler T Lee
    Xenopus laevis arose from hybridization of two different frog species millions of years ago, leading to adaptation of the genetic networks controlling early embryonic development and stem cell induction to balance expression between the genes inherited from each ancestor.
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    Development: Unlocking the microbiome

    Rosana BR Ferreira, L Caetano M Antunes
    Individual species of bacteria and yeast present in the food of wild fruit flies work together to provide the nutrients needed for larval growth.
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    1. Developmental Biology

    Scavenger receptor endocytosis controls apical membrane morphogenesis in the Drosophila airways

    Ana Sofia Pinheiro, Vasilios Tsarouhas ... Christos Samakovlis
    During tracheal morphogenesis, the scavenger receptor Emp senses and responds to luminal cargo levels by initiating apical membrane endocytosis along the longitudinal tube axis to restrict airway elongation.
    1. Developmental Biology
    2. Evolutionary Biology

    Hierarchical morphogenesis of swallowtail butterfly wing scale nanostructures

    Kwi Shan Seah, Vinodkumar Saranathan
    Structured illumination microscopy reveals that the hierarchical development of complex honeycomb-like nanostructures within the lumen of some swallowtail butterfly wing scales proceeds via a novel reorganization of disintegrating F-actin bundles.