Browse our latest Epidemiology and Global Health articles

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    1. Epidemiology and Global Health

    Projected resurgence of COVID-19 in the United States in July—December 2021 resulting from the increased transmissibility of the Delta variant and faltering vaccination

    Shaun Truelove, Claire P Smith ... Cecile Viboud
    Multi-model ensembling projected that the Delta variant would lead to a substantial COVID-19 resurgence in the US, with higher vaccination uptake being a critical factor for limiting transmission and impact between states.
    1. Epidemiology and Global Health

    Impact of the COVID-19 pandemic on breast cancer screening indicators in a Spanish population-based program: a cohort study

    Guillermo Bosch, Margarita Posso ... Francesc Macià
    The COVID-19 pandemic reduced participation in a Spanish population-based breast cancer screening program, especially among regular participants, while other outcomes like recall and cancer detection were not negatively affected by the interruption of screening.
    1. Epidemiology and Global Health
    2. Evolutionary Biology

    Selection for infectivity profiles in slow and fast epidemics, and the rise of SARS-CoV-2 variants

    François Blanquart, Nathanaël Hozé ... Simon Cauchemez
    Selection acting on SARS-CoV-2 variants altering the infectivity profile depends on levels of transmission in the community, and this dependence is used to infer Alpha and Delta variants infectivity profiles.
    1. Computational and Systems Biology
    2. Epidemiology and Global Health

    Osteogenic growth peptide is a potent anti-inflammatory and bone preserving hormone via cannabinoid receptor type 2

    Bitya Raphael-Mizrahi, Malka Attar-Namdar ... Yankel Gabet
    Osteogenic growth peptide displays agonistic activity at CB2.
    1. Epidemiology and Global Health
    2. Medicine

    Type 2 diabetes mellitus accelerates brain aging and cognitive decline: Complementary findings from UK Biobank and meta-analyses

    Botond Antal, Liam P McMahon ... Lilianne R Mujica-Parodi
    Patients with Type 2 diabetes show patterns of neurodegeneration consistent with accelerated brain aging, including impaired cognition and loss of brain volume, which are more severe in those with increased disease duration.
    1. Biochemistry and Chemical Biology
    2. Epidemiology and Global Health

    Association of egg consumption, metabolic markers, and risk of cardiovascular diseases: A nested case-control study

    Lang Pan, Lu Chen ... Liming Li
    The associations of egg consumption with metabolic markers and of these markers with cardiovascular disease (CVD) risk showed opposite directions, which may partially explain the protective effect of moderate egg consumption on CVD in the Chinese population.
    1. Epidemiology and Global Health

    Unbiased proteomics, histochemistry, and mitochondrial DNA copy number reveal better mitochondrial health in muscle of high-functioning octogenarians

    Ceereena Ubaida-Mohien, Sally Spendiff ... Russell T Hepple
    Skeletal muscle from world-class octogenarian athletes, representing a population with very high physical function in advanced age, exhibits greater mass and strength that is associated with overrepresentation of proteins involved in mitochondrial biology and more oxidatively competent muscle fibers.
    1. Epidemiology and Global Health

    Early life infection and proinflammatory, atherogenic metabolomic and lipidomic profiles in infancy: a population-based cohort study

    Toby Mansell, Richard Saffery ... Barwon Infant Study Investigator Group
    More parent-reported infections in the first year of life were associated with metabolic differences linked with cardiovascular and metabolic disease in adulthood, with observational evidence for inflammation partly mediating this relationship.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Mendelian randomization suggests a bidirectional, causal relationship between physical inactivity and adiposity

    Germán D Carrasquilla, Mario García-Ureña ... Tuomas O Kilpeläinen
    Bidirectional causal relationship between higher sedentary time and higher adiposity suggests that decreasing sedentary time is beneficial for weight management, but also that weight loss may help reduce sedentary time.
    1. Epidemiology and Global Health

    Inference of the SARS-CoV-2 generation time using UK household data

    William S Hart, Sam Abbott ... Robin N Thompson
    Updated estimates of the generation time of SARS-CoV-2 infections indicate that the generation time has become shorter.