Browse our latest Epidemiology and Global Health articles

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    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Systematic screening of viral and human genetic variation identifies antiretroviral resistance and immune escape link

    Huyen Nguyen, Christian Wandell Thorball ... The Swiss HIV Cohort Study
    The presence of certain HLA alleles drives the emergence or maintenance of otherwise deleterious drug-resistant mutations in patients living with HIV, even when the patient is antiretroviral treatment naïve.
    1. Epidemiology and Global Health
    2. Medicine

    Mapping the endemicity and seasonality of clinical malaria for intervention targeting in Haiti using routine case data

    Ewan Cameron, Alyssa J Young ... Katherine E Battle
    A demonstration of the power of routine case data and statistical modelling to guide the allocation of anti-malarial interventions in a resource-constrained setting.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Heterogeneity in transmissibility and shedding SARS-CoV-2 via droplets and aerosols

    Paul Z Chen, Niklas Bobrovitz ... Frank X Gu
    Broader case variation in respiratory viral load, and in shedding virus via droplets and aerosols, for SARS-CoV-2 than influenza A(H1N1)pdm09 facilitates greater transmission heterogeneity in the COVID-19 pandemic than the 2009 flu pandemic.
    1. Epidemiology and Global Health
    2. Medicine

    Effects of an urban sanitation intervention on childhood enteric infection and diarrhea in Maputo, Mozambique: A controlled before-and-after trial

    Jackie Knee, Trent Sumner ... Joe Brown
    Onsite sanitation maybe insufficient to interrupt transmission of enteric infections in high-burden urban settings, though risk of some infections may be reduced among children protected from birth.
    1. Epidemiology and Global Health

    Sex differences in biological aging with a focus on human studies

    Sara Hägg, Juulia Jylhävä
    Biological aging processes and age-related diseases demonstrate sexual dimorphism where complex interactions between underlying aging mechanisms and sex chromosomes and hormones are seen in humans and animals.
    1. Epidemiology and Global Health
    2. Genetics and Genomics

    Single mosquito metatranscriptomics identifies vectors, emerging pathogens and reservoirs in one assay

    Joshua Batson, Gytis Dudas ... Hanna Retallack
    How large-scale single mosquito metatranscriptomics can define the mosquito’s complex microbiota and its blood meal sources, and contribute critical epidemiological information needed to control vector borne disease transmission, is shown.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Single-dose BNT162b2 vaccine protects against asymptomatic SARS-CoV-2 infection

    Nick K Jones, Lucy Rivett ... Michael P Weekes
    A fourfold reduction in the rate of asymptomatic SARS-CoV-2 infection in healthcare workers ≥12 days after a single dose of BNT162b2 mRNA COVID-19 vaccine (Pfizer-BioNTech) has been found.
    1. Epidemiology and Global Health
    2. Medicine

    SARS-CoV-2 suppresses anticoagulant and fibrinolytic gene expression in the lung

    Alan E Mast, Alisa S Wolberg ... Daniel Jacobson
    Transcription changes in cells taken from bronchoalveolar fluid of COVID-19 patients indicate severe disruption of coagulation and fibrinolytic pathways in the lung and suggest similar processes in other organs.
    1. Epidemiology and Global Health

    Spatio-temporal associations between deforestation and malaria incidence in Lao PDR

    Francois Rerolle, Emily Dantzer ... Adam Bennett
    Deforestation near villages is associated with short-term increases but long-term decreases in malaria incidence in Lao PDR, highlighting the influence of forest-going populations on malaria transmission in the region.
    1. Epidemiology and Global Health

    Malaria: What happens when forests fall?

    Mercedes Pascual, Andres Baeza
    Combining spatial and temporal data is helping researchers to understand how deforestation influences the risk of malaria.
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