Browse our latest Genetics and Genomics articles

Analysis of data from monozygotic twins reveals that DNA methylation level in human blood cells is reactive to cigarette smoking.

Genetic interaction and biochemical analyses have unveiled the crucial involvement of CTPS in the regulation of adipocyte growth, lipid metabolism, and metabolic adaptation in Drosophila, achieved through activating the PI3K-Akt-SREBP pathway.

Quantification of both viral transcription and progeny production from single influenza-infected cells shows that the cells that produce the most viral RNA often do not produce the most virions.

CD8+ Trm cells' erosion role in oral lichen planus via IFN-γ, TNF-α, and IL17 cytokines has been revealed, addressing a gap in recurrent erosion studies.

Increased production of ether lipids is required to extend lifespan in response to metformin, phenformin, and multiple, distinct, longevity-promoting manipulations, illuminating the possibility that raising ether lipid levels represents a new therapeutic strategy to support healthy aging.

How biologically relevant chemical information can be genetically maintained and conveyed in complex sex pheromonal profiles.

The long-range resection machinery is dispensable for homologous recombination between closely linked repeats but is necessary for DNA damage checkpoint activation which is associated with interchromosomal recombination.

Combining computational and experimental approaches reveals that the loss of a maternal transcription factor influences sex-biased differential splicing in the early zygotic transcriptome at genes that are critical for normal developmental processes.

SUMOylated PCNA and the Elg1 PCNA unloader interact with the CST complex to coordinate DNA replication and telomere length maintenance.

The transcriptional cofactor HPK-1 (homeodomain-interacting protein kinase) functions as a key regulator of multiple proteostatic stress responses, each originating from discrete neuronal subtypes within the Caenorhabditis elegans nervous system to preserve neuronal health and maintain organismal proteostasis during normal aging.