Browse our latest Genetics and Genomics articles

Associations between plasma protein levels and DNA methylation patterns can be used to predict the onset of age-related chronic disease.

Various genotoxic stresses trigger widespread aggregation of abundant, liquid-liquid phase separation-prone proteins, suggesting that genotoxic stress is a potential driver of disease-associated protein aggregation.

An ethnically robust pipeline for inferring mitochondrial DNA copy number from genotyping arrays was developed and applied to the UKBiobank, elucidating several common and rare loci in genes involved in the synthesis, maintenance, and organization of mitochondrial DNA.

Adenine and cytosine base editing of highly homologous HBG proximal promoter identifies novel target sites that result in adult to fetal globin switching without causing 4.9 kb large deletions.

Nuclei of the true slime mold Physarum polycephalum are continuously shuttled within the cytoplasmic flow across the gigantic syncytium, yet Physarum can establish and maintain gene expression heterogeneity between different structures of the organism.

Two distinct genetic biocontrol methods work synergistically to yield a novel approach in the fight against pest organisms.

The third causative gene ZNF862 was novelly identified for hereditary gingival fibromatosis in a large Chinese family.

DunedinPACE is a novel DNA methylation biomarker of the pace of biological aging for intervention trials and natural experiment studies investigating how the rate of aging may be changed by behavioral or drug therapy, or by environmental modification.

The in vitro and in vivo characterization of two nanobody/NanoTag pairs in the Drosophila system provides a variety of assays for protein detection and manipulation.

Pioneering activity may be a property of all transcription factors with sufficient affinity for their targets rather than a property of specific classes of transcription factors.