Browse our latest Genetics and Genomics articles

The RNA binding protein FMRP regulates the synthesis of synaptic and nuclear proteins within different compartments of a neuron.

The maintenance of diverse cell identities might be coordinated through the interaction between widely acting transcriptional corepressors and cell-specific transcription factors to repress undesired gene expression in a cell-type-specific manner.

Methylomic and trancriptomic analyses demonstrate the regulation of the toll-like receptor 4 inflammatory gene expression, an essential actor of the fetal membrane weakening at the end of pregnancy.

Collaborative transcription factors (TFs) exhibit a dominant pattern of a relaxed range of spacing and substantial tolerance of spacing alterations resulting from naturally occurring insertions and deletions in comparison to genetic variants directly affecting TF binding sites.

The spread of herbicide resistance in one of the most problematic weeds in North America occurs through both recent, repeated mutational origins and gene flow across an international network of agricultural fields.

Following exposure of Leishmania culture promastigotes to DNA stress, single-cell RNA sequencing reveals discrete clusters of cells associated with efficient generation of hybrids between different species and strains in vitro marked by expression of the ancestral gamete fusogen HAP2.

Differences in the usage of DNA repair pathways may give rise to the unique patterns of Y-linked mutations that, together with natural selection, shape rapid Y chromosome evolution.

The Arabidopsis N6-methyladenosine (m⁶A) binding proteins ECT2 and ECT3 act redundantly in the cytoplasm to regulate m⁶A-containing mRNAs whose abundances are reduced in ect2/ect3/ect4 knockout plants although the locations of their polyadenylation sites remain unaffected, contrary to currently held beliefs.

The Arabidopsis N6-methyladenosine (m⁶A)-binding protein ECT2 binds to m⁶A in the canonical RR[m⁶A]CH motif, not a plant-specific motif as previously thought, and its intrinsically disordered region contributes to mRNA binding via contacts with U-rich motifs.

Mating phenotypes are diverse in Schizosaccharomyces pombe and the natural variation can impact the spread of wtf meiotic drivers.