Browse our latest Immunology and Inflammation articles

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    1. Immunology and Inflammation
    2. Computational and Systems Biology

    A predictive systems vaccinology framework enables rational optimization of MVA-based vaccines

    Vincent Deman, Philippe Castera ... Anne-Sophie Beignon
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Computational and Systems Biology
    2. Immunology and Inflammation

    +Clonal stochasticity in early NK cell response to mouse cytomegalovirus is generated by mature subsets of varying proliferative ability

    Darren Wethington, Saeed Ahmad ... Jayajit Das
    Stochastic fluctuations play an important role in the MCMV-induced NK cell clonal expansion that ultimately gives rise to memory NK cells.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    The C3–C3aR axis modulates trained immunity in alveolar macrophages

    Alexander P Earhart, Alberto E Lopez ... Hrishikesh S Kulkarni
    Complement component C3, a key component of immune responses at mucosal sites, affects alveolar macrophage reprogramming via the C3aR.
    Version of Record
    Short Report
    • Important
    • Convincing
    1. Immunology and Inflammation

    An IL-21R STAT hypomorph circumvents functional redundancy in germinal center responses

    Christoph Jandl, Joanna Warren ... Cecile King
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Immunology and Inflammation

    Role of mast cells in endomicrobial sepsis revisited: Mast cell-deficient mice show normal immunological protection

    Thorsten B Feyerabend, Fabienne Schochter ... Hans-Reimer Rodewald
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Immunology and Inflammation

    Bcl11b dose-dependently regulates positive selection of CD8 T cells to the virtual memory fate

    Tom Sidwell, Ellen V Rothenberg
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Immunology and Inflammation
    2. Cancer Biology

    Cutaneous inflammation accelerates the premalignant expansion of melanocytes bearing oncogenic mutations

    Diana Tran, Anastasiia Vaska ... Morgan Huse
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Immunology and Inflammation

    CD56dimCD16dim NK cells are the dominant effector cells against HIV-infected primary T-cells

    William Howell, Courtney Branch ... Edward Barker
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Bacterial and viral gut microbiome alterations characterize microbiome-immune-pathophysiology axes in sickle cell disease

    Zachary N Flamholz, Jennifer De Los Santos ... Libusha Kelly
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Immunology and Inflammation

    Sphingosine 1-phosphate receptor-1 signaling enhances neutrophil survival while suppressing inflammation and bacterial host defense functions

    Yueh-Chien Lin, Takahiro Seno ... Timothy Hla
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
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